Valerij Talagayev

1. SOVA, Matej, DOLŠAK, Ana, TALAGAYEV, Valerij, ŠRIBAR, Dora, HOLZE, Janine, GOBEC, Stanislav, WOLBER, Gerhard, WEINDL, Guenther. Design, synthesis and optimization of novel small molecule toll-like receptor 8 modulators based on a 6-(trifluoromethyl)pyrimidine-2-amine scaffold. V: Book of abstracts. [S. l.]: [s. n.], 2022. Str. 198, p166, ilustr. https://www.efmc-ismc.org/v2/data/1661849465EFMC-ISMC-Book-Web-HD3.pdf. [COBISS.SI-ID 121088771]

2. TALAGAYEV, Valerij, STRAŠEK BENEDIK, Nika, MATZIOL, Troy, ŠRIBAR, Dora, DOLŠAK, Ana, WOLBER, Gerhard, SOVA, Matej, WEINDL, Günther. A novel approach of toll-like receptor dynamics application for structure optimization through 3d pharmacophore analysis. V: Book of abstracts. 2022. Str. 98, p057, ilustr. https://www.efmc.info/cust_events.php?langue=english&cle_menus=1187970268. [COBISS.SI-ID 169686787]

3. SOVA, Matej, STRAŠEK BENEDIK, Nika, DOLŠAK, Ana, ŠVAJGER, Urban, TALAGAYEV, Valerij, MATZIOL, Troy, HOLZE, Janine, WEINDL, Günther, WOLBER, Gerhard, GOBEC, Stanislav. Novel classes of small-molecule toll-like receptors 7 and 8 modulators : design, synthesis and biological evaluation. V: Book of abstracts. [S. l.]: [s. n.], 2023. Str. 312, p232, ilustr. https://www.efmc-asmc.org/content.php?langue=english&cle_menus=1238917879. [COBISS.SI-ID 164229635]

4. MATZIOL, Troy, TALAGAYEV, Valerij, SLOKAN, Tjaša, SOVA, Matej, WOLBER, Gerhard, WEINDL, Günther. Exploration and biological evaluation of novel isoxazole-based small-molecule Toll-like receptor 8 antagonists. V: 7th TOLL 2024 Conference, Rotterdam, the Netherlands from April 17-20, 2024 : abstract e-book : oral abstracts in selected abstract sessions. Rotterdam: [s. n.], 2024. Str. 269, p190. https://www.toll2024.org/wp-content/uploads/2024/04/TOLL-2024-Abstract-E-Book.pdf?_gl=1*t4jfpl*_up*MQ..*_ga*MTczMzg1NjE5My4xNzQ0MDk5Njgw*_ga_QGRMM07VZS*MTc0NDA5OTY3Ny4xLjAuMTc0NDA5OTY3Ny4wLjAuMA.., https://www.toll2024.org/abstract-e-book/. [COBISS.SI-ID 231771907]

5. MATZIOL, Troy, TALAGAYEV, Valerij, SLOKAN, Tjaša, STRAŠEK BENEDIK, Nika, HOLZE, Janine, SOVA, Matej, WOLBER, Gerhard, WEINDL, Günther. Discovery of novel isoxazole-based small-molecule Toll-like receptor 8 antagonists. Journal of medicinal chemistry. [Online ed.]. 2025, vol. 68, no. 4, str. 4888-4907, ilustr. ISSN 1520-4804. https://pubs.acs.org/doi/full/10.1021/acs.jmedchem.4c03148, Repozitorij Univerze v Ljubljani – RUL, DOI: 10.1021/acs.jmedchem.4c03148. [COBISS.SI-ID 235973123]
projekt: This work was funded bythe Slovenian Research and Innovation Agency (research corefunding no. P1-0208, grant to M.S. J1-4417, bilateral projectgrant BI-DE/23-24-011, and a grant to N.S.B.) and supportedby the German Research Foundation to G.W. and G.W. (grantRA 895/16-1).

6. STRAŠEK BENEDIK, Nika, TALAGAYEV, Valerij, MATZIOL, Troy, DOLŠAK, Ana, SOSIČ, Izidor, WEINDL, Günther, WOLBER, Gerhard, SOVA, Matej. Optimization of 6-(trifluoromethyl)pyrimidine derivatives as TLR8 antagonists. Acta pharmaceutica. 2025, vol. 75, iss. 2, str. 159-183, ilustr., graf. prikazi. ISSN 1846-9558. https://acta.pharmaceutica.farmaceut.org/wp-content/uploads/2025/06/15925.pdf, Repozitorij Univerze v Ljubljani – RUL, DOI: 10.2478/acph-2025-0011. [COBISS.SI-ID 240657155]
projekt: This work was funded by the Slovenian Research and Innovation Agency (research core funding No. P1-0208, grant to M.S. J1-4417, bilateral project grant BIDE/23-24-011, and a grant to N.S.B.).

7. STRAŠEK BENEDIK, Nika, LUKIĆ, David, SLOKAN, Tjaša, DOLŠAK, Ana, ŠVAJGER, Urban, KRANJC BREZAR, Simona, TALAGAYEV, Valerij, WOLBER, Gerhard, ČEMAŽAR, Maja, SOSIČ, Izidor, SOVA, Matej. Synthesis and structure-activity relationship study of novel quinazolin-4(3H)-one derivatives as Toll-like receptor 7 and 8 agonists with immunomodulatory activity. European journal of medicinal chemistry. Jan. 2026, vol. 302, art. no. 118360, 1-24 str., ilustr. ISSN 1768-3254. https://www.sciencedirect.com/science/article/pii/S0223523425011250?via%3Dihub, DOI: 10.1016/j.ejmech.2025.118360. [COBISS.SI-ID 257484035]