Jan Krönke

1. SOSIČ, Izidor, STEINEBACH, Christian, LINDNER, Stefanie, BRICELJ, Aleša, KOHL, Franziska, NG, Yuen Lam Dora, KRÖNKE, Jan, GÜTSCHOW, Michael. A chemical toolbox for cereblon-directed PROTACS. V: Book of abstracts : Joint Symposium on Medicinal Chemistry Frontiers. [S. l.]: [s. n.], 2019. Str. 172. https://www.medchemfrontiers.org/programme. [COBISS.SI-ID 4734065]

2. STEINEBACH, Christian, SOSIČ, Izidor, LINDNER, Stefanie, BRICELJ, Aleša, KOHL, Franziska, NG, Yuen Lam Dora, MONSCHKE, Marius, WAGNER, Karl G., KRÖNKE, Jan, GÜTSCHOW, Michael. A MedChem toolbox for cereblon-directed PROTACs. MedChemComm. 2019, vol. 10, iss. 6, str. 1037-1041, ilustr. ISSN 2040-2503. https://pubs.rsc.org/en/content/articlelanding/2019/md/c9md00185a#!divAbstract, https://pubs.rsc.org/en/content/articlepdf/2019/md/c9md00185a, DOI: 10.1039/C9MD00185A. [COBISS.SI-ID 4723057]

3. STEINEBACH, Christian, NG, Yuen Lam Dora, SOSIČ, Izidor, LINDNER, Stefanie, KRÖNKE, Jan, GÜTSCHOW, Michael. Four E3 Ligases, one Target : towards novel CDK6 protacs. V: Book of abstracts : 2nd Alpine Winter Conference on Medicinal and Synthetic Chemistry, St. Anton, Austria, 19 - 23, 2020. [S. l.: s. n.], 2020. Str. 35, ilustr. https://www.alpinewinterconference.org/v2/data/1579181858BookAbstracts-Web.pdf. [COBISS.SI-ID 4875121]

4. STEINEBACH, Christian, FERBER, D., NG, Yuen Lam Dora, BRICELJ, Aleša, JAMALI, Mina, KUCHTA, Robert, SOSIČ, Izidor, HARTMANN, Marcus, KRÖNKE, Jan, GÜTSCHOW, Michael. Design, synthesis and biomedical investigation of new E3 ligase modulators : poster at Frontiers in Medicinal Chemistry, March 8 - 10, 2021, online : annual meeting. [COBISS.SI-ID 56817667]

5. BRICELJ, Aleša, NG, Yuen Lam Dora, FERBER, D., KUCHTA, Robert, MÜLLER, Sina, MONSCHKE, Marius, WAGNER, Karl G., KRÖNKE, Jan, SOSIČ, Izidor, GÜTSCHOW, Michael, STEINEBACH, Christian. Influence of linker attachment points on the stability and neosubstrate degradation of cereblon ligands. ACS Medicinal Chemistry Letters. 2021, vol. 12, iss. 11, str. 1733-1738, ilustr. ISSN 1948-5875. https://pubs.acs.org/doi/10.1021/acsmedchemlett.1c00368, DOI: 10.1021/acsmedchemlett.1c00368. [COBISS.SI-ID 81287683]
projekt: P1-0208 Grant J1-2485 to I.S.; financer: This work was supported by the DFG (Emmy-Noether Program Kr-3886/2-1 and SFB-1074 to J.K.), the ARRS, and the German Academic Scholarship Foundation

6. STEINEBACH, Christian, NG, Yuen Lam Dora, BRICELJ, Aleša, SOSIČ, Izidor, KRÖNKE, Jan, GÜTSCHOW, Michael. PROTAC-mediated inactivation of e3 ligases : from tools to cancer treatment. V: Book of abstracts. 2021. Str. 156, po96, ilustr. https://www.efmc-ymcs.org/v2/data/1630930688BookYMCS-Virtual-HD.pdf. [COBISS.SI-ID 76063491]

7. STEINBACHER, Christian, NG, Yuen Lam Dora, BRICELJ, Aleša, SOSIČ, Izidor, KRÖNKE, Jan, GÜTSCHOW, Michael. Protac-mediated inactivation of e3 ligases: from tools to cancer treatment. V: Book of abstracts. 2021. Str. 291, m052. https://www.efmc-ismc.org/v2/data/1630081893EFMC-ISMC-BookOfAbstracts-webHD.pdf. [COBISS.SI-ID 74933251]

8. SOSIČ, Izidor, STEINEBACH, Christian, BRICELJ, Aleša, NG, Y.L.D., GOBEC, Martina, KRÖNKE, Jan, PIETERS, Roland J., ANDERLUH, Marko, GÜTSCHOW, Michael. PROTACS as tools for the modulation of pharmacological targets : presented at early bird sessions on 45th FEBS Congress, Molecules of Life: Towards New Horizons, Ljubljana, Slovenia, July 3-8, 2021. FEBS open bio. 2021, vol. 11, suppl. s1, str. 100. ISSN 2211-5463. https://febs.onlinelibrary.wiley.com/doi/epdf/10.1002/2211-5463.13206, DOI: 10.1002/2211-5463.13206. [COBISS.SI-ID 70178051]

9. BRICELJ, Aleša, NG, Yuen Dora, JANSEN, Jacqueline, KRÖNKE, Jan, GÜTSCHOW, Michael, STEINEBACH, Christian, SOSIČ, Izidor. Heterobifunctional E3 ligase recruiters for PAN-degradation of inhibitor of apoptosis proteins. V: Book of abstracts. [S. l.]: [s. n.], 2022. Str. 131, p022. https://www.efmc-ismc.org/v2/data/1661849465EFMC-ISMC-Book-Web-HD3.pdf. [COBISS.SI-ID 121076739]

10. MURGAI, Arunima, SOSIČ, Izidor, GOBEC, Martina, LEMNITZER, Patricia, PROJ, Matic, WITTENBURG, Sophie, VOGET, Rabea, GÜTSCHOW, Michael, KRÖNKE, Jan, STEINEBACH, Christian. Targeting the deubiquitinase USP7 for degradation with PROTACs. Chemical communications. [Online ed.]. 2022, vol. 58, iss. 63, str. 8858-8861, ilustr. ISSN 1364-548X. https://pubs.rsc.org/en/content/articlelanding/2022/cc/d2cc02094g, DOI: 10.1039/D2CC02094G. [COBISS.SI-ID 115213571]
projekt: P1-0208; financer: ARRS
projekt: J1-2485; financer: ARRS
projekt: Kr-3886/2-1; financer: DFG
projekt: SFB-1074; financer: DFG
projekt: CA214608; financer: Costa action
projekt: CA218278; financer: Cost action

11. KUCHTA, Robert, HEIM, Christopher, HERRMANN, Alexander, MAIWALD, Samuel, NG, Yuen Lam Dora, SOSIČ, Izidor, KEULER, Tim, KRÖNKE, Jan, GÜTSCHOW, Michael, HARTMANN, Marcus D., STEINEBACH, Christian. Accessing three-branched high-affinity cereblon ligands for molecular glue and protein degrader design. RSC chemical biology. 2023, vol. 4, iss. 3, str. 229-234, ilustr. ISSN 2633-0679. https://pubs.rsc.org/en/content/articlelanding/2023/cb/d2cb00223j, Repozitorij Univerze v Ljubljani – RUL, DOI: 10.1039/D2CB00223J. [COBISS.SI-ID 136507395]
projekt: Kr-3886/2-1; financer: DFG
projekt: SFB-1074; financer: DFG
projekt: P1-0208; financer: ARRS
projekt: J1-2485; financer: ARRS
projekt: CA214608; financer: NIH
projekt: CA218278; financer: NIH

12. BRICELJ, Aleša, NG, Yuen Dora, JANSEN, Jacqueline A., MURGAI, Arunima, KRÖNKE, Jan, PETER, Kirsten, DONOVAN, Katherine A., GÜTSCHOW, Michael, STEINEBACH, Christian, SOSIČ, Izidor. Battle of the E3 ligases : using heteroprotacs to induce pan-iap degradation. V: JAKOPIN, Žiga (ur.), TOMAŠIČ, Tihomir (ur.). Crossing the Boundaries of Medicinal Chemistry : book of abstracts : University of Ljubljana, Faculty of Pharmacy, September 28, 2023. Ljubljana: Fakulteta za farmacijo, 2023. Str. 7-8, ilustr. ISBN 978-961-6378-95-6. https://www.ffa.uni-lj.si/docs/default-source/e-knjige/book-of-abstracts---crossing-the-boundaries-of-medicinal-chemistry.pdf?sfvrsn=2. [COBISS.SI-ID 173398787]

13. BRICELJ, Aleša, NG, Yuen Lam Dora, JANSEN, Jacqueline A., MURGAI, Arunima, KRÖNKE, Jan, PETER, Kirsten, DONOVAN, Katherine A., GÜTSCHOW, Michael, STEINEBACH, Christian, SOSIČ, Izidor. Heterobifunctional E3 ligase recruiters enable pan-degradation of inhibitor of apoptosis proteins. V: Book of abstracts. [S. l.]: [s. n.], 2023. Str. 123, p033, ilustr. https://www.efmc-asmc.org/content.php?langue=english&cle_menus=1238917879. [COBISS.SI-ID 164222467]

14. BRICELJ, Aleša, NG, Yuen Lam Dora, JANSEN, Jacqueline A., MURGAI, Arunima, KRÖNKE, Jan, PETER, Kirsten, DONOVAN, Katherine A., GÜTSCHOW, Michael, STEINEBACH, Christian, SOSIČ, Izidor. Heterobifunctional E3 ligase recruiters enable pan-degradation of inhibitor of apoptosis proteins. V: Book of abstracts. 2022. Str. 33, oc12, ilustr. https://www.efmc.info/cust_events.php?langue=english&cle_menus=1187970268. [COBISS.SI-ID 169682435]

15. NG, Yuen Lam Dora, BRICELJ, Aleša, JANSEN, Jacqueline A., MURGAI, Arunima, PETER, Kirsten, DONOVAN, Katherine A., GÜTSCHOW, Michael, KRÖNKE, Jan, STEINEBACH, Christian, SOSIČ, Izidor. Heterobifunctional ligase recruiters enable pan-degradation of inhibitor of apoptosis proteins. Journal of medicinal chemistry. [Online ed.]. 2023, vol. 66, iss. 7, str. 4703-4733, ilustr. ISSN 1520-4804. https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01817, Repozitorij Univerze v Ljubljani – RUL, DOI: 10.1021/acs.jmedchem.2c01817. [COBISS.SI-ID 147303683]
nagrada: Članek je prejel Dekanovo nagrado, 2023

16. BRICELJ, Aleša, NG, Yuen Dora, JANSEN, Jacqueline A., KRÖNKE, Jan, GÜTSCHOW, Michael, ANDERLUH, Marko, STEINEBACH, Christian, SOSIČ, Izidor. Lessons learned from successes and struggles in implementing protac methodology for a panel of proteins involved in malignancies. V: Book of abstracts. Medicinal Chemistry Frontiers 2023 Boston, MA, United States June 10-13, 2023. [S. l.]: [s. n.], 2023. Str. 104, p011. https://www.medchemfrontiers.org/auth.php?langue=english&cle_menus=1049119092&ant_file_redirect=https%3A%2F%2Fwww.medchemfrontiers.org%2Fcontent.php%3Flangue%3Denglish%26cle_menus%3D1238917781. [COBISS.SI-ID 158405379]

17. WITTENBURG, Sophie, MURGAI, Arunima, KRÖNKE, Jan, SOSIČ, Izidor, GÜTSCHOW, Michael, STEINEBACH, Christian. Design and synthesis of novel USP7-targeting protacs. V: Book of abstracts : 4th Alpine Winter Conference on Medicinal and Synthetic Chemistry, St. Anton, Austria, January 28-February 1, 2024. [S. l.: s. n.], 2024. Str. 110, p025, ilustr. https://www.alpinewinterconference.org/auth.php?langue=english&cle_menus=1049119092&ant_file_redirect=content.php%3Flangue%3Denglish%26amp%3Bcle_menus%3D1238918051. [COBISS.SI-ID 199448067]

18. STEINEBACH, Christian, WITTENBURG, Sophie, MURGAI, Arunima, SOSIČ, Izidor, KRÖNKE, Jan, GÜTSCHOW, Michael. Discovery of PROTACs directed against the deubiquitinase USP7. V: Protein Degradation in Focus : A Special Symposium to Celebrate the Opening of CeTPD in Dundee 19th – 22nd May 2024 University of Dundee, UK : programme & abstracts. A Special Symposium to Celebrate the Opening of CeTPD in Dundee 19th – 22nd May 2024 University of Dundee. Dundee: University of Dundee, UK, 2024. Str. 176. https://www.dundee.ac.uk/events/protein-degradation-focus-symposium. [COBISS.SI-ID 195892483]

19. SPÜLBECK, Sophie, ZULEEG, Maximilian R., KRÖNKE, Jan, SOSIČ, Izidor, GÜTSCHOW, Michael, STEINEBACH, Christian, et al. Design and synthesis of solubility-enhanced VHL-protacs targeting USP7. V: Book of abstracts. X EFMC-ASMC International Symposium on Advances in Synthetic and Medicinal Chemistry, Porto, Portugal, August 31-September 4, 2025. Str. 453, p367, ilustr. https://www.efmc-asmc.org/poster-sessions. [COBISS.SI-ID 288585731]

20. SIEVERS, Johannes, NG, Yuen Lam Dora, BRICELJ, Aleša, LU, Feiteng, KROLS, Simon, KRÖNKE, Jan, VAN CALENBERGH, Serge, GÜTSCHOW, Michael, SOSIČ, Izidor, STEINEBACH, Christian. Medicinal chemistry approaches towards BCL-2-selective degraders. V: Book of abstracts : EFMC-ASMC International Symposium on Advances in Synthetic and Medicinal Chemistry Porto, Portugal August 31-September 4, 2025. [S. l.: s. n.], 2025. Str. 438, p352, ilustr. https://www.efmc-asmc.org/programme. [COBISS.SI-ID 250753539]