Yuen Lam Dora Ng

1. SOSIČ, Izidor, STEINEBACH, Christian, LINDNER, Stefanie, BRICELJ, Aleša, KOHL, Franziska, NG, Yuen Lam Dora, KRÖNKE, Jan, GÜTSCHOW, Michael. A chemical toolbox for cereblon-directed PROTACS. V: Book of abstracts : Joint Symposium on Medicinal Chemistry Frontiers. [S. l.]: [s. n.], 2019. Str. 172. https://www.medchemfrontiers.org/programme. [COBISS.SI-ID 4734065]

2. STEINEBACH, Christian, SOSIČ, Izidor, LINDNER, Stefanie, BRICELJ, Aleša, KOHL, Franziska, NG, Yuen Lam Dora, MONSCHKE, Marius, WAGNER, Karl G., KRÖNKE, Jan, GÜTSCHOW, Michael. A MedChem toolbox for cereblon-directed PROTACs. MedChemComm. 2019, vol. 10, iss. 6, str. 1037-1041, ilustr. ISSN 2040-2503. https://pubs.rsc.org/en/content/articlelanding/2019/md/c9md00185a#!divAbstract, https://pubs.rsc.org/en/content/articlepdf/2019/md/c9md00185a, DOI: 10.1039/C9MD00185A. [COBISS.SI-ID 4723057]

3. STEINEBACH, Christian, NG, Yuen Lam Dora, SOSIČ, Izidor, LINDNER, Stefanie, KRÖNKE, Jan, GÜTSCHOW, Michael. Four E3 Ligases, one Target : towards novel CDK6 protacs. V: Book of abstracts : 2nd Alpine Winter Conference on Medicinal and Synthetic Chemistry, St. Anton, Austria, 19 - 23, 2020. [S. l.: s. n.], 2020. Str. 35, ilustr. https://www.alpinewinterconference.org/v2/data/1579181858BookAbstracts-Web.pdf. [COBISS.SI-ID 4875121]

4. STEINEBACH, Christian, NG, Yuen Lam Dora, SOSIČ, Izidor, LEE, Chih-Shia, CHEN, Sirui, LINDNER, Stefanie, PHUONG, Vu Lan, BRICELJ, Aleša, HASCHEMI, Reza, MONSCHKE, Marius, et al. Systematic exploration of different E3 ubiquitin ligases : an approach towards potent and selective CDK6. Chemical science. 2020, vol. 11, str. 3474-3486, ilustr. ISSN 2041-6539. https://pubs.rsc.org/en/content/articlelanding/2020/sc/d0sc00167h#!divAbstract, https://pubs.rsc.org/en/content/articlepdf/2020/sc/d0sc00167h, http://www.rsc.org/suppdata/d0/sc/d0sc00167h/d0sc00167h1.pdf, DOI: 10.1039/D0SC00167H. [COBISS.SI-ID 4889969]

5. STEINEBACH, Christian, FERBER, D., NG, Yuen Lam Dora, BRICELJ, Aleša, JAMALI, Mina, KUCHTA, Robert, SOSIČ, Izidor, HARTMANN, Marcus, KRÖNKE, Jan, GÜTSCHOW, Michael. Design, synthesis and biomedical investigation of new E3 ligase modulators : poster at Frontiers in Medicinal Chemistry, March 8 - 10, 2021, online : annual meeting. [COBISS.SI-ID 56817667]

6. BRICELJ, Aleša, NG, Yuen Lam Dora, FERBER, D., KUCHTA, Robert, MÜLLER, Sina, MONSCHKE, Marius, WAGNER, Karl G., KRÖNKE, Jan, SOSIČ, Izidor, GÜTSCHOW, Michael, STEINEBACH, Christian. Influence of linker attachment points on the stability and neosubstrate degradation of cereblon ligands. ACS Medicinal Chemistry Letters. 2021, vol. 12, iss. 11, str. 1733-1738, ilustr. ISSN 1948-5875. https://pubs.acs.org/doi/10.1021/acsmedchemlett.1c00368, DOI: 10.1021/acsmedchemlett.1c00368. [COBISS.SI-ID 81287683]
projekt: P1-0208 Grant J1-2485 to I.S.; financer: This work was supported by the DFG (Emmy-Noether Program Kr-3886/2-1 and SFB-1074 to J.K.), the ARRS, and the German Academic Scholarship Foundation

7. STEINEBACH, Christian, NG, Yuen Lam Dora, BRICELJ, Aleša, SOSIČ, Izidor, KRÖNKE, Jan, GÜTSCHOW, Michael. PROTAC-mediated inactivation of e3 ligases : from tools to cancer treatment. V: Book of abstracts. 2021. Str. 156, po96, ilustr. https://www.efmc-ymcs.org/v2/data/1630930688BookYMCS-Virtual-HD.pdf. [COBISS.SI-ID 76063491]

8. STEINBACHER, Christian, NG, Yuen Lam Dora, BRICELJ, Aleša, SOSIČ, Izidor, KRÖNKE, Jan, GÜTSCHOW, Michael. Protac-mediated inactivation of e3 ligases: from tools to cancer treatment. V: Book of abstracts. 2021. Str. 291, m052. https://www.efmc-ismc.org/v2/data/1630081893EFMC-ISMC-BookOfAbstracts-webHD.pdf. [COBISS.SI-ID 74933251]

9. KUCHTA, Robert, HEIM, Christopher, HERRMANN, Alexander, MAIWALD, Samuel, NG, Yuen Lam Dora, SOSIČ, Izidor, KEULER, Tim, KRÖNKE, Jan, GÜTSCHOW, Michael, HARTMANN, Marcus D., STEINEBACH, Christian. Accessing three-branched high-affinity cereblon ligands for molecular glue and protein degrader design. RSC chemical biology. 2023, vol. 4, iss. 3, str. 229-234, ilustr. ISSN 2633-0679. https://pubs.rsc.org/en/content/articlelanding/2023/cb/d2cb00223j, Repozitorij Univerze v Ljubljani – RUL, DOI: 10.1039/D2CB00223J. [COBISS.SI-ID 136507395]
projekt: Kr-3886/2-1; financer: DFG
projekt: SFB-1074; financer: DFG
projekt: P1-0208; financer: ARRS
projekt: J1-2485; financer: ARRS
projekt: CA214608; financer: NIH
projekt: CA218278; financer: NIH

10. BRICELJ, Aleša, NG, Yuen Lam Dora, JANSEN, Jacqueline A., MURGAI, Arunima, KRÖNKE, Jan, PETER, Kirsten, DONOVAN, Katherine A., GÜTSCHOW, Michael, STEINEBACH, Christian, SOSIČ, Izidor. Heterobifunctional E3 ligase recruiters enable pan-degradation of inhibitor of apoptosis proteins. V: Book of abstracts. [S. l.]: [s. n.], 2023. Str. 123, p033, ilustr. https://www.efmc-asmc.org/content.php?langue=english&cle_menus=1238917879. [COBISS.SI-ID 164222467]

11. BRICELJ, Aleša, NG, Yuen Lam Dora, JANSEN, Jacqueline A., MURGAI, Arunima, KRÖNKE, Jan, PETER, Kirsten, DONOVAN, Katherine A., GÜTSCHOW, Michael, STEINEBACH, Christian, SOSIČ, Izidor. Heterobifunctional E3 ligase recruiters enable pan-degradation of inhibitor of apoptosis proteins. V: Book of abstracts. 2022. Str. 33, oc12, ilustr. https://www.efmc.info/cust_events.php?langue=english&cle_menus=1187970268. [COBISS.SI-ID 169682435]

12. NG, Yuen Lam Dora, BRICELJ, Aleša, JANSEN, Jacqueline A., MURGAI, Arunima, PETER, Kirsten, DONOVAN, Katherine A., GÜTSCHOW, Michael, KRÖNKE, Jan, STEINEBACH, Christian, SOSIČ, Izidor. Heterobifunctional ligase recruiters enable pan-degradation of inhibitor of apoptosis proteins. Journal of medicinal chemistry. [Online ed.]. 2023, vol. 66, iss. 7, str. 4703-4733, ilustr. ISSN 1520-4804. https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01817, Repozitorij Univerze v Ljubljani – RUL, DOI: 10.1021/acs.jmedchem.2c01817. [COBISS.SI-ID 147303683]
nagrada: Članek je prejel Dekanovo nagrado2023

13. STEINEBACH, Christian, BRICELJ, Aleša, MURGAI, Arunima, SOSIČ, Izidor, BISCHOF, Luca, NG, Yuen Lam Dora, HEIM, Christopher, PROJ, Matic, KOŠMRLJ, Janez, SCHNAKENBURG, Gregor, et al. Leveraging ligand affinity and properties : discovery of novel benzamide-type cereblon binders for the design of PROTACs. Journal of medicinal chemistry. [Online ed.]. 2023, vol. 66, iss. 21, str. 14513-14543, ilustr. ISSN 1520-4804. https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00851, DOI: 10.1021/acs.jmedchem.3c00851. [COBISS.SI-ID 171061251]

14. BRICELJ, Aleša, NG, Yuen Lam Dora, GOBEC, Martina, KUCHTA, Robert, HU, Wanyi, JAVORNIK, Špela, ROŽIČ, Miha, GÜTSCHOW, Michael, ZHENG, Guangrong, SOSIČ, Izidor, et al. Design, synthesis, and evaluation of BCL-2 targeting PROTACs. Chemistry : a European journal. [Online ed.]. 2024, vol. 30, iss. 45, [article no. e202400430], 8 str., ilustr. ISSN 1521-3765. https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202400430, DOI: 10.1002/chem.202400430. [COBISS.SI-ID 197511171]
projekt: We acknowledge support by the SlovenianResearch Agency (ARRS) (Program P1-0208 andGrant J1-2485 to I.S.), the German ResearchFoundation (DFG) (Kr-3886/8 and SFB-1074 toJ.K.; STE 3140/1-1 to C.S.), and the NationalInstitute of Health (NIH) (R01 CA241191 to G.Z.).

15. SIEVERS, Johannes, NG, Yuen Lam Dora, BRICELJ, Aleša, LU, Feiteng, KROLS, Simon, KRÖNKE, Jan, VAN CALENBERGH, Serge, GÜTSCHOW, Michael, SOSIČ, Izidor, STEINEBACH, Christian. Medicinal chemistry approaches towards BCL-2-selective degraders. V: Book of abstracts : EFMC-ASMC International Symposium on Advances in Synthetic and Medicinal Chemistry Porto, Portugal August 31-September 4, 2025. [S. l.: s. n.], 2025. Str. 438, p352, ilustr. https://www.efmc-asmc.org/programme. [COBISS.SI-ID 250753539]