Špela Gubič

1. GUBIČ, Špela, KUZMA, Larisa, JERIČ, Niko. Šolska pravila nekoč in danes : dodatni pouk pri zgodovini. Murska Sobota: Osnovna šola II, 2009. 37 f., ilustr. [COBISS.SI-ID 8083507]

2. GUBIČ, Špela. Biomasa : energetska učinkovitost ogrevanja v vasi Krog : [raziskovalna naloga]. Murska Sobota: Osnovna šola II Murska Sobota, 2010. 44 f., ilustr. [COBISS.SI-ID 8086067]

3. GRILEC, David, GUBIČ, Špela, ROUDI, Luka. Javni promet v Murski Soboti : avtobusni in železniški promet : raziskovalna naloga iz geografije. Murska Sobota: OŠ II, 2010. 63 f., ilustr., graf. prikazi. [COBISS.SI-ID 8081203]

4. MAKOTER, Karla, GUBIČ, Špela, KREFT, Sara. Vrednotenje interakcij med (biološkimi) makromolekulami z encimskoimunskimi testi : protitelesa proti leptinskemu receptorju kot potencialna nova biološka zdravila : raziskovalna naloga. Ljutomer: Gimnazija Franca Miklošiča, [2014]. III f., 65 f., graf. prikazi. [COBISS.SI-ID 14457651]
nagrada: Srebrno priznanje

5. GUBIČ, Špela, KREFT, Sara, MAKOTER, Karla. Vrednotenje interakcij med biološkimi makromolekulami z encimskimi imunskimi testi = Evaluation of interactions between biological macro-molecules with enzyme-linked immunosorbent assay. V: PLEVNIK, Miha (ur.). 44. Krkine nagrade : znanost povezuje : zbornik povzetkov : 24. simpozij, Novo mesto, 17. oktober 2014. Novo mesto: Krka, [2014]. Str. 79. [COBISS.SI-ID 3907697]

6. FOIS, Marzia, GUBIČ, Špela, SHI, Xiaoyi, SZABÓ, Ildikó, PARDO A., Luis, PETERLIN-MAŠIČ, Lucija, TOMAŠIČ, Tihomir. Novel mitochondrial KV 1.3 inhibitors : design, synthesis and biological evaluation. V: 7th RSC/SCI Symposium on Ion Channels as Therapeutic Targets, Monday-Tuesday, 27th - 28th March 2023, Genome Campus, Cambridge, UK : Conference Handbook. Cambridge: Royal Society of Chemistry, 2023. Str. 52, p25. https://cdn.eventsforce.net/files/ef-px6ci6a56tzs/website/234/ion_channels_2023_handbook_final.pdf. [COBISS.SI-ID 183847171]

7. GUBIČ, Špela, HITI, Luka. Pregled uporabe mace (Lepidium meyenii) pri različnih zdravstvenih stanjih = Overview of maca (Lepidium meyenii) uses in different health conditions. Farmacevtski vestnik : strokovno glasilo slovenske farmacije. [Tiskana izd.]. dec. 2018, letn. 69, št. 5, str. 352-358, ilustr. ISSN 0014-8229. http://www.dlib.si/details/URN:NBN:SI:doc-7BWSKEL2. [COBISS.SI-ID 32960039]

8. GUBIČ, Špela. Sinteza 6-substituiranih tetrahidropirolo[1,2-a]pirazinskih zaviralcev encima InhA = Synthesis of 6-substituted tetrahydropyrrolo[1,2-a]pyrazine type of InhA inhibitors : enoviti magistrski študijski program Farmacija. Ljubljana: [Š. Gubič], 2019. XII, 61 f., ilustr. https://repozitorij.uni-lj.si/IzpisGradiva.php?id=109059. [COBISS.SI-ID 4767089]

9. TOPLAK, Žan, HENDRICKX, Louise Antonia, GUBIČ, Špela, MOŽINA, Štefan, ŽEGURA, Bojana, ŠTERN, Alja, NOVAK, Matjaž, SHI, Xiaoyi, TOMAŠIČ, Tihomir, PETERLIN-MAŠIČ, Lucija, et al. 3D pharmacophore-based discovery of novel Kv10.1 inhibitors with antiproliferative activity. Cancers. 2021, vol. 13, iss. 6, str. 1-24, ilustr. ISSN 2072-6694. https://www.mdpi.com/2072-6694/13/6/1244, Repozitorij Univerze v Ljubljani – RUL. [COBISS.SI-ID 55144451]

10. GUBIČ, Špela, HENDRICKX, Louise Antonia, TOPLAK, Žan, STERLE, Maša, PEIGNEUR, Steve, TOMAŠIČ, Tihomir, PARDO A., Luis, TYTGAT, Jan, ZEGA, Anamarija, PETERLIN-MAŠIČ, Lucija. Discovery of K V 1.3 ion channel inhibitors : medicinal chemistry approaches and challenges. Medicinal research reviews. 2021, 41, iss. 4, str. 2423-2473, ilustr. ISSN 1098-1128. https://onlinelibrary.wiley.com/doi/10.1002/med.21800?fbclid=IwAR1_DHtmR-noxar9IpT79drKbH91UeWJFXQMC32EeX_GlotbKhrZvp2MjJI, Repozitorij Univerze v Ljubljani – RUL, DOI: 10.1002/med.21800. [COBISS.SI-ID 61605123]

11. GUBIČ, Špela, TOMAŠIČ, Tihomir, TOPLAK, Žan, HENDRICKX, Louise Antonia, TYTGAT, Jan, PARDO A., Luis, PETERLIN-MAŠIČ, Lucija. New potassium ion channels kv1.3 and kv10.1 inhibitors as new anticancer compounds. V: Book of abstracts. 2021. Str. 364, t025. https://www.efmc-ismc.org/v2/data/1630081893EFMC-ISMC-BookOfAbstracts-webHD.pdf. [COBISS.SI-ID 74946819]

12. GUBIČ, Špela, HENDRICKX, Louise Antonia, SHI, Xiaoyi, TOPLAK, Žan, VAN THEEMSCHE, Kenny M., LOPES PINHEIRO-JUNIOR, Ernesto, PEIGNEUR, Steve, LABRO, Alain J., TOMAŠIČ, Tihomir, PETERLIN-MAŠIČ, Lucija, et al. Design of new potent and selective thiophene-based Kv1.3 inhibitors and their potential for anticancer activity. V: OBREZA, Aleš (ur.), et al. 9th BBBB International Conference on Pharmaceutical Sciences : Pharma sciences of tomorrow : book of abstracts : Ljubljana, Slovenia, 15th-17th September, 2022. Ljubljana: Slovensko farmacevtsko društvo: Fakulteta za farmacijo, 2022. Str. 271-273, p65, ilustr. ISBN 978-961-94230-4-2. https://bbbb2022.sfd.si/wp-content/uploads/2020/08/9th-bbbb-conference-book-of-abstracts.pdf. [COBISS.SI-ID 122001667]

13. GUBIČ, Špela, HENDRICKX, Louise Antonia, SHI, Xiaoyi, TOPLAK, Žan, MOŽINA, Štefan, VAN THEEMSCHE, Kenny M., LOPES PINHEIRO-JUNIOR, Ernesto, PEIGNEUR, Steve, TOMAŠIČ, Tihomir, PETERLIN-MAŠIČ, Lucija, et al. Design of new potent and selective thiophene-based Kv1.3 inhibitors and their potential for anticancer activity. Cancers. 2022, vol. 14, no. 11, art. no. 2595, str. 1-20, ilustr. ISSN 2072-6694. https://www.mdpi.com/2072-6694/14/11/2595, Repozitorij Univerze v Ljubljani – RUL, DOI: 10.3390/cancers14112595. [COBISS.SI-ID 109409795]
nagrada: Mentorica Lucija Peterlin Mašič, somentor Tihomir Tomašič
projekt: J1-9192, N1-0098, P1-0245 CELSA projekt; financer: ARRS
projekt: 813834-PHIONIC-H2020-MSCA-ITN-2018; financer: Max-Planck Society and from the European Union through Horizon 2020
projekt: PDM/19/164; financer: KU Leuven

14. PETERLIN-MAŠIČ, Lucija, TOMAŠIČ, Tihomir, GUBIČ, Špela, PARDO A., Luis, TYTGAT, Jan, ARCANGELI, Annarosa. Heteroaryl benzamide potassium channel Kv1.3 inhibitors : LU patent application LU501902, 22. April 2022. Luxembourg: LU Luxembourg Intellectual Property Office, 2022. 125 str., ilustr. [COBISS.SI-ID 121003011]

15. TOPLAK, Žan, HENDRICKX, Louise Antonia, GUBIČ, Špela, TYTGAT, Jan, PARDO A., Luis, PETERLIN-MAŠIČ, Lucija, TOMAŠIČ, Tihomir. In silico discovery and optimisation of voltage-gated potassium channel kv10.1 inhibitors with antiproliferative activity. V: Book of abstracts. [S. l.]: [s. n.], 2022. Str. 153, p069, ilustr. https://www.efmc-ismc.org/v2/data/1661849465EFMC-ISMC-Book-Web-HD3.pdf. [COBISS.SI-ID 121079811]

16. TOPLAK, Žan, HENDRICKX, Louise Antonia, GUBIČ, Špela, TYTGAT, Jan, PARDO A., Luis, PETERLIN-MAŠIČ, Lucija, TOMAŠIČ, Tihomir. In silico discovery and optimisation of voltage-gated potassium channel kv10.1 inhibitors with antiproliferative activity. V: OBREZA, Aleš (ur.), et al. 9th BBBB International Conference on Pharmaceutical Sciences : Pharma sciences of tomorrow : book of abstracts : Ljubljana, Slovenia, 15th-17th September, 2022. Ljubljana: Slovensko farmacevtsko društvo: Fakulteta za farmacijo, 2022. Str. 280-281, p69, ilustr. ISBN 978-961-94230-4-2. https://bbbb2022.sfd.si/wp-content/uploads/2020/08/9th-bbbb-conference-book-of-abstracts.pdf. [COBISS.SI-ID 121892611]
projekt: P1-0208; financer: ARRS
projekt: NI-0098; financer: ARRS
projekt: CELSA 005-1/2017; financer: University of Ljubljana
projekt: 813834-PHIONIC-H2020- MSCA-ITN-2018; financer: Eur. Union through Horizon 2020 research and innovation program under the Marie Skłodowska‐Curie grant agreement

17. GUBIČ, Špela. Načrtovanje in sinteza novih zaviralcev napetostno odvisnih kalijevih kanalov KV 1.3 in KV 10.1 s protitumornim delovanjem = Design and synthesis of novel voltage-gated potassium channel KV 1.3 and KV 10.1 inhibitors with anticancer activity : doktorska disertacija. Ljubljana: [Š. Gubič], 2022. IX, 384 str., ilustr. [COBISS.SI-ID 133516291]
projekt: N1-0098; financer: ARRS

18. GUBIČ, Špela. Načrtovanje novih tiofenskih zaviralcev KV1.3 in njihov potencial za protirakavo delovanje : predavanje v okviru Tedna Univerze v Ljubljani na Fakulteti za farmacijo, Ljubljana, 30. november 2022. [COBISS.SI-ID 131518211]

19. GUBIČ, Špela, TOPLAK, Žan, SHI, Xiaoyi, DERNOVŠEK, Jaka, HENDRICKX, Louise Antonia, LOPES PINHEIRO-JUNIOR, Ernesto, PEIGNEUR, Steve, TYTGAT, Jan, PARDO A., Luis, PETERLIN-MAŠIČ, Lucija, TOMAŠIČ, Tihomir. New diarylamine KV10.1 inhibitors and their anticancer potential. Pharmaceutics. [Online ed.]. 2022, vol. 14, iss. 9, art. 1963, 27 str., ilustr. ISSN 1999-4923. https://www.mdpi.com/1999-4923/14/9/1963, Repozitorij Univerze v Ljubljani – RUL, DOI: 10.3390/pharmaceutics14091963. [COBISS.SI-ID 121841667]
projekt: N1-0098 Odkrivanje in mehanizem delovanja novih spojin vodnic hEag1 kalijevih kanalov s protirakavim delovanjem; financer: ARRS
projekt: P1-0208 Farmacevtska kemija: načrtovanje, sinteza in vrednotenje učinkovin; financer: ARRS
projekt: 813834-PHIONIC-H2020-MSCA-ITN2018; financer: Max-Planck Society and European Union through Horizon 2020

20. GORNIK, Tjaša. Sinteza benzamidnih zaviralcev napetostno odvisnih kalijevih ionskih kanalov Kv1.3 = Synthesis of benzamide-based inhibitors of the Kv1.3 voltage gated potassium ion channel : enoviti magistrski študijski program Farmacija. Ljubljana: [T. Gornik], 2022. XI, 56 f., ilustr. [COBISS.SI-ID 99406339]

21. FOIS, Marzia, GUBIČ, Špela, SHI, Xiaoyi, SZABÓ, Ildikó, PARDO A., Luis, PETERLIN-MAŠIČ, Lucija, TOMAŠIČ, Tihomir. Development of benzamide-based mitochondrial kV 1.3 inhibitors as anticancer agents : [poster communications]. V: MedChem2023 : XII Paul Ehrlich PhD NetWork in Medicinal Chemistry, Thessaloniki, Greece, July 16th – 18th 2023 : book of abstracts. [S. l.]: [s. n.], 2023. Str. 60, pc-7. https://medchem2023.com/abstract-book/. [COBISS.SI-ID 183845123]

22. GUBIČ, Špela, MONTALBANO, Alberto, SALA, Cesare, BECCHETTI, Andrea, HENDRICKX, Louise Antonia, VAN THEEMSCHE, Kenny M., LOPES PINHEIRO-JUNIOR, Ernesto, ILAŠ, Janez, TOMAŠIČ, Tihomir, PETERLIN-MAŠIČ, Lucija, et al. Immunosuppressive effects of new thiophene-based K▫$_V$▫1.3 inhibitors. European journal of medicinal chemistry. [Print ed.]. 2023, vol. 259, art. 115561, 17 str., ilustr. ISSN 0223-5234. https://www.sciencedirect.com/science/article/pii/S0223523423005275, Repozitorij Univerze v Ljubljani – RUL, DOI: 10.1016/j.ejmech.2023.115561. [COBISS.SI-ID 156924419]

23. PETERLIN-MAŠIČ, Lucija, TOMAŠIČ, Tihomir, GUBIČ, Špela, PARDO A., Luis. Mitochondriotropic benzamide potassium channel K v1.3 inhibitors : International application published under the patent cooperation treaty (PCT) WO 2023/203185 A1, 2023-10-26. Geneve: WIPO, 2023. 107 str., ilustr. https://worldwide.espacenet.com/patent/search/family/082214354/publication/WO2023203185A1?q=pn%3DWO2023203185A1. [COBISS.SI-ID 121005315]

24. GUBIČ, Špela. Načrtovanje in sinteza novih zaviralcev napetostno odvisnih kalijevih kanalov KV 1.3 in KV 10.1 s protitumornim delovanjem = Design and synthesis of novel voltage-gated potassium channel KV 1.3 and KV 10.1 inhibitors with anticancer activity. V: PLEVNIK, Miha (ur.), OBERSTAR FALKNER, Maja, GORJUP, Simona. 53. Krkine nagrade = 53nd Krka Prizes : zbornik povzetkov = book of abstracts : 33. simpozij = 33rd symposium : [Novo mesto, 20. oktober 2023]. Novo mesto: Krka, [2023]. Str. 69. [COBISS.SI-ID 171851011]

25. FOIS, Marzia, GUBIČ, Špela, SHI, Xiaoyi, SZABÓ, Ildikó, PARDO A., Luis, PETERLIN-MAŠIČ, Lucija, TOMAŠIČ, Tihomir. Novel mitochondrial kv1.3 inhibitors : design, synthesis and biological evaluation. V: JAKOPIN, Žiga (ur.), TOMAŠIČ, Tihomir (ur.). Crossing the Boundaries of Medicinal Chemistry : book of abstracts : University of Ljubljana, Faculty of Pharmacy, September 28, 2023. Ljubljana: Fakulteta za farmacijo, 2023. Str. 16. ISBN 978-961-6378-95-6. https://www.ffa.uni-lj.si/docs/default-source/e-knjige/book-of-abstracts---crossing-the-boundaries-of-medicinal-chemistry.pdf?sfvrsn=2. [COBISS.SI-ID 173404419]

26. MIHELIČ, Lara. Sinteza 3-tiofenskih zaviralcev mitohondrijskih ionskih kanalčkov K▫$_v$▫1.3 kot protirakavih učinkovin. Ljubljana: [L. Mihelič], 2023. 68 f., ilustr. [COBISS.SI-ID 157037827]

27. FOIS, Marzia, GUBIČ, Špela, SHI, Xiaoyi, SZABÓ, Ildikó, PARDO A., Luis, PETERLIN-MAŠIČ, Lucija, TOMAŠIČ, Tihomir. New series of benzamide-based mitochondrial kv1.3 inhibitors with anticancer activity. V: KRAJNC, Alen (ur.), GOBEC, Martina (ur.). Brunching with soft- and research skills at UL FFA: unlocking your full potential : 1st UL FFA Graduate Student Research Symposium : book of abstracts : University of Ljubljana, Faculty of Pharmacy, April 2024. Online ed. Ljubljana: Faculty of Pharmacy, 2024. Str. 24, ilustr. ISBN 978-961-6378-97-0. https://www.ffa.uni-lj.si/docs/default-source/e-knjige/brunching-with-soft-and-research-skills-at-ul-ffa.pdf?sfvrsn=2. [COBISS.SI-ID 198096643]

28. GUBIČ, Špela, FOIS, Marzia, DŽAJIĆ, Ivan, KOLOŠA, Katja, ŠTERN, Alja, OMERZEL, Maša, BOŽIČ, Tim, MARKELC, Boštjan, JESENKO, Tanja, ČEMAŽAR, Maja, ŽEGURA, Bojana, KOSJEK, Tina, COTMAN, Andrej Emanuel, TOMAŠIČ, Tihomir, PETERLIN-MAŠIČ, Lucija, et al. New mitochondrial ▫$K_V$▫1.3 conjugates are potent and specific inducers of apoptosis in cancer models. Biomedicine & pharmacotherapy. Feb. 2026, vol. 195, [article no.] 118996, str. 1-18, ilustr. ISSN 1950-6007. https://www.sciencedirect.com/science/article/pii/S0753332226000284, DiRROS - Digitalni repozitorij raziskovalnih organizacij Slovenije, DOI: 10.1016/j.biopha.2026.118996. [COBISS.SI-ID 266063619]