Davide Benedetto Tiz

1. BENEDETTO TIZ, Davide. Sintesi e caratterizzazione di nuovi inibitori di CK-1 : tesi sperimentale in chimica farmaceutica. Trieste: D. Benedetto Tiz, 2014. VI, 81 str., ilustr. https://thesis.units.it/handle/20.500.12072/13266?mode=simple. [COBISS.SI-ID 145252867]

2. BENEDETTO TIZ, Davide, KIKELJ, Danijel, ZIDAR, Nace. Novel N-phenyl-4,5-dibromopyrrolamides and N-phenyl-3,4-dichloro-5- methylpyrrolamides targeting DNA Gyrase B and topoisomerase IV. In: COST ACTION CA15135 : book of the abstracts : multi-target paradigm for innovative ligand identification in the drug discovery process (MuTaLig) : poly-pharmacology expanding Paul Ehrlich's magic bullet concept. First Annual Meeting, Università della Svizzera Italiana - USI - Lugano (CH) - July 21, 22, 2016. [S. l.: s. n. ], 2016. Str. 70, ilustr. [COBISS.SI-ID 4253297]

3. BENEDETTO TIZ, Davide, KIKELJ, Danijel, ZIDAR, Nace. Novel N-phenyl-4,5-dibromopyrroloamides and N-phenyl-3,4-dichloro-5-methylpyrrolamides targeting DNA gyrase B and toposiomerase IV. In: Cost Action CM1407, 1st Training School, Belgrade, 24-26 September 2016 : in vitro evaluation of compounds with anticancer potential. [S. l.: s. n.], 2016. Str. 18. [COBISS.SI-ID 4217201]

4. BARANČOKOVA, Michaela, ILAŠ, Janez, TOMAŠIČ, Tihomir, ZIDAR, Nace, LAMUT, Andraž, BENEDETTO TIZ, Davide, TAMMELA, Päivi, FELICI, Antonio, GARRIDO, Vanesa, KIKELJ, Danijel. Discovery of novel gyrase B and gyrase B/topoisomerase IV (ParE) dual inhibitors with in vitro antibacterial activity : oral presentations. In: Book of abstracts. 10th Joint Meeting on Medicinal Chemistry, Dubrovnik (Srebreno), Croatia, June 25-28, 2017. Dubrovnik: Croatian Chemical Society, 2017. Str. 63, ilustr. ISBN 978-953-55232-8-4. http://www.jmmc2017.hr/images/Book_of_Abstracts_web.pdf. [COBISS.SI-ID 4394609]

5. BENEDETTO TIZ, Davide, KIKELJ, Danijel, ZIDAR, Nace. Novel N-phenyl-4,5-dibromopyrroloamides and N-phenyl-3,4-dichloro-5-methylpyrrolamides targeting DNA gyrase B and topoisomerase IV. In: 7th Meeting of Paul Ehrlich MedChem Euro-PhD network, Wien, Austria, August 25-27, 2017. [S. l.]: [s. n.], 2017. https://www.medchemeurophd.eu/. [COBISS.SI-ID 4375921]

6. BENEDETTO TIZ, Davide, BARANČOKOVA, Michaela, SKOK, Žiga, ILAŠ, Janez, TAMMELA, Päivi, KIKELJ, Danijel, ZIDAR, Nace. Design, synthesis and evaluation of novel GyrB/ParE inhibitors. In: Book of abstracts : VIII Meeting of the Paul Ehrlich EuroPhD Network, Porto, Portugal 12th - 14th July, 2018. Porto: [s. n. ], 2018. Str. 45. http://paulehrlichphd2018.org/wp-content/uploads/2018/07/Book-of-abstracts-1.pdf. [COBISS.SI-ID 4547441]

7. DURCIK, Martina, LOVISON, Denise, SKOK, Žiga, DURANTE CRUZ, Cristina, TAMMELA, Päivi, TOMAŠIČ, Tihomir, BENEDETTO TIZ, Davide, DRASKOVITS, Gábor, NYERGES, Ákos, PÁL, Csaba, ILAŠ, Janez, PETERLIN-MAŠIČ, Lucija, KIKELJ, Danijel, ZIDAR, Nace. New N-phenylpyrrolamide DNA gyrase B inhibitors : optimisation of efficacy and antibacterial activity. European journal of medicinal chemistry. [Print ed.]. June 2018, vol. 154, str. 117-132, ilustr. ISSN 0223-5234. https://www.sciencedirect.com/science/article/pii/S022352341830415X, DOI: 10.1016/j.ejmech.2018.05.011. [COBISS.SI-ID 4504945]
project: P1-0208; funder: ARRS
project: 277001; funder: Academy of Finland
project: 304697; funder: Academy of Finland
project: 312503; funder: Academy of Finland
project: H2020-ERC-2014-CoG 648364 Resistance Evolution; funder: European Research Council
project: 2.3.2-15-2016-00020; funder: Wellcome Trust (to C.P.), and GINOP (MolMedEx TUMORDNS)
project: 2.3.2- 15-2016-00014; funder: GINOP (EVOMER)

8. BENEDETTO TIZ, Davide, KIKELJ, Danijel, ZIDAR, Nace. Overcoming problems of poor drug penetration into bacteria : challenges and strategies for medicinal chemists. Expert opinion on drug discovery. 2018, vol. 13, iss. 6, str. 497-507. ISSN 1746-0441. https://www.tandfonline.com/doi/full/10.1080/17460441.2018.1455660, DOI: 10.1080/17460441.2018.1455660. [COBISS.SI-ID 4505201]

9. BENEDETTO TIZ, Davide, SKOK, Žiga, DURCIK, Martina, TOMAŠIČ, Tihomir, PETERLIN-MAŠIČ, Lucija, ILAŠ, Janez, ZEGA, Anamarija, DRASKOVITS, Gábor, REVESZ, T., NYERGES JÓZSEF, Ákos, PÁL, Csaba, DURANTE CRUZ, Cristina, TAMMELA, Päivi, ŽIGON, Dušan, KIKELJ, Danijel, ZIDAR, Nace. An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors. European journal of medicinal chemistry. [Print ed.]. Apr. 2019, vol. 167, str. 269-290, ilustr. ISSN 0223-5234. https://www.sciencedirect.com/science/article/pii/S022352341930114X?via%3Dihub#!, DOI: 10.1016/j.ejmech.2019.02.004. [COBISS.SI-ID 4686961]
project: P1-0208; funder: ARRS
project: 277001; funder: Academy of Finland
project: 304697; funder: Academy of Finland
project: 312503; funder: Academy of Finland
project: H2020-ERC-2014-CoG 64836 Resistance Evolution; funder: European Research Council
project: 2.3.2-15-2016-00020; funder: GINOP
project: 2.3.2-15-2016-00014; funder: GINOP
project: funder: PhD fellowship from the Boehringer Ingelheim Fonds

10. BENEDETTO TIZ, Davide. Razvoj novih N-fenilpirolamidov kot zaviralcev DNA-giraze in topoizomeraze IV = Discovery of novel N-phenylpyrrolamides as inhibitors of DNA gyrase and topoisomerase IV : doctoral dissertation. Ljubljana: [D. Benedetto Tiz], 2019. XVIII, 339 str., ilustr. Repository of the University of Ljubljana – RUL , http://www.dlib.si/details/URN:NBN:SI:doc-O5PR09XF. [COBISS.SI-ID 4726641]

11. BENEDETTO TIZ, Davide. Razvoj novih N-fenilpirolamidov kot zaviralcev DNA-giraze in topoizomeraze IV = Discovery of novel N-phenylpyrrolamides as inhibitors of DNA gyrase and topoisomerase IV. In: PLEVNIK, Miha (ed.). 49. Krkine nagrade : znanost povezuje : zbornik povzetkov : 29. simpozij, Novo mesto, 18. oktober 2019. Novo mesto: Krka, 2019. Str. 54. [COBISS.SI-ID 4845425]

12. GRIECO, Ilenia, BISSARO, Maicol, BENEDETTO TIZ, Davide, PEREZ, Daniel I., PEREZ, Conception, MARTINEZ, Ana, REDENTI, Sara, MARIOTTO, Elena, BORTOLOZZI, Roberta, GIAMPIETRO, Viola, COZZA, Giorgio, SPALLUTO, Giampiero, MORO, Stefano, FEDERICO, Stephanie. Developing novel classes of protein kinase CK1δ inhibitors by fusing [1,2,4]triazole with different bicyclic heteroaromatic systems. European journal of medicinal chemistry. [Print ed.]. 2021, vol. 216, [article no.] 113331, str. 1-27, ilustr. ISSN 0223-5234. https://www.sciencedirect.com/science/article/pii/S022352342100180X?via%3Dihub, DOI: 10.1016/j.ejmech.2021.113331. [COBISS.SI-ID 145122563]

13. COTMAN, Andrej Emanuel, GUÉRIN, Thomas, KOVAČEVIĆ, Ivana, BENEDETTO TIZ, Davide, DURCIK, Martina, FULGHERI, Federica, MOŽINA, Štefan, SECCI, Daniela, STERLE, Maša, ILAŠ, Janez, ZEGA, Anamarija, ZIDAR, Nace, PETERLIN-MAŠIČ, Lucija, TOMAŠIČ, Tihomir, KIKELJ, Danijel, et al. Practical synthesis and application of halogen-doped pyrrole building blocks. ACS omega. 2021, vol. 6, no. 14, str. 9723-9730, ilustr. ISSN 2470-1343. https://pubs.acs.org/doi/10.1021/acsomega.1c00331, https://pubs.acs.org/doi/pdf/10.1021/acsomega.1c00331, DOI: 10.1021/acsomega.1c00331. [COBISS.SI-ID 58134275]

14. BENEDETTO TIZ, Davide, BAGNOLI, Luana, ROSATI, Ornelio, MARINI, Francesca, SANTI, Claudio, SANCINETO, Luca. FDA-approved small molecules in 2022 : clinical uses and their synthesis. Pharmaceutics. [Online ed.]. 2022, vol. 14, iss. 11, [article no.] 2538, str. 1-19, ilustr. ISSN 1999-4923. https://www.mdpi.com/1999-4923/14/11/2538, DOI: 10.3390/pharmaceutics14112538. [COBISS.SI-ID 139606531]

15. BENEDETTO TIZ, Davide, MANGIAVACCHI, Francesca, SANCINETO, Luca, SCIMMI, Cecilia, SANTI, Claudio. Halogenated Se-based compounds as inhibitors of the Main Protease of SARSCov2 virus : presented at the Faculty of Chemistry, Tamka 12, Halchem, HalchemX, Poland, 5th September 2022. [COBISS.SI-ID 142563075]

16. BENEDETTO TIZ, Davide, BAGNOLI, Luana, ROSATI, Ornelio, MARINI, Francesca, SANCINETO, Luca, SANTI, Claudio. New halogen-containing drugs approved by FDA in 2021 : an overview on their syntheses and pharmaceutical use. Molecules. 2022, vol. 27, iss. 5, [article no.] 1643, str. 1-23, ilustr. ISSN 1420-3049. https://www.mdpi.com/1420-3049/27/5/1643, DOI: 10.3390/molecules27051643. [COBISS.SI-ID 139558147]

17. BENEDETTO TIZ, Davide, MANGIAVACCHI, Francesca, SANCINETO, Luca, SCIMMI, Cecilia, SANTI, Claudio. Synthesis of Se-based compounds as inhibitors of the Main Protease of SARS-Cov2 virus and their Interaction with glutathione. In: CIERPIAŁ, Tomasz (ed.). 9th Workshop of the multidisciplinary network SeS Redox and Catalysis : 8-10 September 2022, Łódź (Poland). Łódź: [s. n.], 2022. Str. 41. ISBN 978-83-66536-72-2. [COBISS.SI-ID 142358787]

18. ŽULA, Matej, GRILC, Miha, KOSTINJUK, Andrij Olegovič, TOFANI, Giorgio, JASIUKAITYTE, Edita, ROČNIK, Tina, CHOWDARI, Ramesh Kumar, LAVRIČ, Žan, TERŽAN, Janvit, HOČEVAR, Brigita, JAKOB, Ana, RAKIĆ, Emilija, POMEROY, Brett, CAJNKO, Miša Mojca, VICENTE, Filipa A., MARINIČ, Dana, OBERLINTNER, Ana, NOVAK, Uroš, BENEDETTO TIZ, Davide, HUŠ, Matej, LIKOZAR, Blaž. Biorefining twin transition : digitalisation for bio-based chemicals/materials - discovery, design and optimisation. Chimia. 2023, vol. 77, no. 12, str. 816–826, ilustr. ISSN 2673-2424. https://www.chimia.ch/chimia/article/view/2023_816, DiRROS - Digital repository of Slovenian research organizations, DOI: 10.2533/chimia.2023.816. [COBISS.SI-ID 180155651]

19. BENEDETTO TIZ, Davide, TOFANI, Giorgio, VICENTE, Filipa A., LIKOZAR, Blaž. Chemical synthesis of monolignols : traditional methods, recent advances, and future challenges in sustainable processes. Antioxidants. 2024, vol. 13, iss. 11, [article no.] 1387, str. 1-26, ilustr. ISSN 2076-3921. https://www.mdpi.com/2076-3921/13/11/1387, DiRROS - Digital repository of Slovenian research organizations, DOI: 10.3390/antiox13111387. [COBISS.SI-ID 218137603]

20. COTMAN, Andrej Emanuel, DURCIK, Martina, BENEDETTO TIZ, Davide, FULGHERI, Federica, SECCI, Daniela, STERLE, Maša, MOŽINA, Štefan, SKOK, Žiga, ZIDAR, Nace, ZEGA, Anamarija, ILAŠ, Janez, PETERLIN-MAŠIČ, Lucija, TOMAŠIČ, Tihomir, KIKELJ, Danijel, et al. Discovery and Hit-to-Lead Optimization of Benzothiazole scaffold-based DNA gyrase inhibitors with potent activity against Acinetobacter baumannii and Pseudomonas aeruginosa. Journal of medicinal chemistry. [Online ed.]. 2023, vol. 66, no. 2, str. 1380-1425, ilustr. ISSN 1520-4804. https://pubs.acs.org/doi/full/10.1021/acs.jmedchem.2c01597, Repository of the University of Ljubljana – RUL , DOI: 10.1021/acs.jmedchem.2c01597. [COBISS.SI-ID 138544899]
project: P1-0208 Farmacevtska kemija: načrtovanje, sinteza in vrednotenje učinkovin; funder: ARRS
project: J1-3030 MTAvsAMR: novi večtarčni antibiotiki proti večkratno odpornim bakterijam; funder: ARRS
project: J1- 3031 Razvoj novih zaviralcev bakterijskih topoizomeraz za boj proti odpornim infekcijam; funder: ARRS
project: BB/J014524/1; funder: iCASE studentship funded by BBSRC and Redx Pharma Plc
project: 110072/Z/15/ Z; funder: Investigator Award from the Wellcome Trust
project: BB/ P012523/1

21. BENEDETTO TIZ, Davide, PODLIPNIK, Črtomir. Illicit street drugs?! Recent trends and chemistry. Clinical case reports international. Jul. 2023, vol. 7, [article no.] 1570, str. 1-11. ISSN 2638-4558. https://www.clinicalcasereportsint.com/open-access/illicit-street-drugs-recent-trends-and-chemistry-9722.pdf. [COBISS.SI-ID 160451331]

22. BENEDETTO TIZ, Davide, VICENTE, Filipa A., KROFLIČ, Ana, LIKOZAR, Blaž. Lignin-based covalent adaptable network polymers─when bio-based thermosets meet recyclable by design. ACS sustainable chemistry & engineering. Sep. 25, 2023, vol. 11, iss. 38, str. 13836–13867, ilustr. ISSN 2168-0485. https://pubs.acs.org/doi/10.1021/acssuschemeng.3c03248, DiRROS - Digital repository of Slovenian research organizations, DOI: 10.1021/acssuschemeng.3c03248. [COBISS.SI-ID 163491331]

23. BENEDETTO TIZ, Davide, VICENTE, Filipa A., LIKOZAR, Blaž. Lignin-based covalent adaptable networks (CANs) : a possible replacement for fossil-based thermosets. In: BILIŠIKOV, Nikola (ed.). Book of abstracts and programme : Solid-State Science & Research, Zagreb, 28 - 30 June 2023. Str. 59, ilustr. ISBN 978-953-7941-48-2. https://drive.google.com/file/d/1Cp1XNoxnVxPTpc-7EX0pLmUyipgW-Z34/view. [COBISS.SI-ID 159173891]

24. BENEDETTO TIZ, Davide, VICENTE, Filipa A., LIKOZAR, Blaž. Lignin-based covalent adaptable networks (CANs) : a potential substitute for thermosets made of fossil fuels. In: PRIMOŽIČ, Lea (ed.), SIMMONS, Amy Noel (ed.), FÁBIÁN, Gertrud (ed.). IRIC 2023 : interdisciplinary solutions for sustainable buildings : book of abstracts : 13-14 September 2023, Izola, Slovenia. Electronic ed. Izola: Innorenew CoE; Koper: University of Primorska Press, 2023. Str. 6. InnoRenew CoE International Conference series. ISBN 978-961-293-258-9, ISBN 978-961-293-259-6. ISSN 2784-6679. https://www.hippocampus.si/ISBN/978-961-293-258-9.pdf, https://innorenew.eu/iric2023/. [COBISS.SI-ID 167834627]

25. VICENTE, Filipa A., TOFANI, Giorgio, BENEDETTO TIZ, Davide, JASIUKAITYTE, Edita, KROFLIČ, Ana, LIKOZAR, Blaž. Lignin-derived covalent adaptable networks (CANs) : a sustainable approach to versatile material design. In: SILVA, Ana Maria Alves Queiroz da (ed.). 14th International Chemical and Biological Engineering Conference : (CHEMPOR-2023) : book of abstracts : [...] Bragança - Portugal, from the 12th to the 15th of September, 2023. Bragança: Instituto Politécnico de Bragança, 2023. Str. 264-265. https://chempor2023.events.chemistry.pt/important-information, https://bitok.datastore.pt/scimeet-prod/cms/chempor2023.events.chemistry.pt/433e1fb4-754e-4d97-8eec-0c4793a786bf/CHEMPOR2023_BookofAbstracts_September10th_Version1.pdf. [COBISS.SI-ID 169105411]

26. BENEDETTO TIZ, Davide, PODLIPNIK, Črtomir. A review of FDA-approved antiparasitic drugs in USA for sheep and goats : their synthesis and pharmaceutical use. Trends in pharmaceutical sciences. 2023, vol.9, iss. 3, str. 221-236, ilustr. ISSN 2423-5652. https://tips.sums.ac.ir/article_49531.html, DOI: 10.30476/tips.2023.98660.1193. [COBISS.SI-ID 172545283]

27. BENEDETTO TIZ, Davide, BAGNOLI, Luana, ROSATI, Ornelio, MARINI, Francesca, SANCINETO, Luca, SANTI, Claudio. Top selling (2026) small molecule orphan drugs : a journey into their chemistry. International journal of molecular sciences. 2023, vol. 24, iss. 2, [article no.] 930, str. 1-21, ilustr. ISSN 1422-0067. https://www.mdpi.com/1422-0067/24/2/930, DOI: 10.3390/ijms24020930. [COBISS.SI-ID 139616771]

28. ZIDAR, Nace, ONALI, Alessia, PERŠOLJA, Peter, BENEDETTO TIZ, Davide, DERNOVŠEK, Jaka, SKOK, Žiga, DURCIK, Martina, COTMAN, Andrej Emanuel, HRAST RAMBAHER, Martina, ZEGA, Anamarija, PETERLIN-MAŠIČ, Lucija, ILAŠ, Janez, TOMAŠIČ, Tihomir, KIKELJ, Danijel, et al. Improved N-phenylpyrrolamide inhibitors of DNA gyrase as antibacterial agents for high-priority bacterial strains. European journal of medicinal chemistry. 2024, vol. 278, 19 str., ilustr. ISSN 1768-3254. https://www.sciencedirect.com/science/article/pii/S0223523424007049, Repository of the University of Ljubljana – RUL , DOI: 10.1016/j.ejmech.2024.116823. [COBISS.SI-ID 206357251]
project: This work was supported by the Slovenian Research Agency (Grant No. P1-0208, J1-3021 and J1-3031) and by the Research Council of Finland (Grant No. 321551).

29. COTMAN, Andrej Emanuel, FULGHERI, Federica, PIGA, Martina, PERŠOLJA, Peter, BENEDETTO TIZ, Davide, SKOK, Žiga, DURCIK, Martina, STERLE, Maša, DERNOVŠEK, Jaka, ZEGA, Anamarija, PETERLIN-MAŠIČ, Lucija, ILAŠ, Janez, TOMAŠIČ, Tihomir, KIKELJ, Danijel, ZIDAR, Nace, et al. New N-phenylpyrrolamide inhibitors of DNA gyrase with improved antibacterial activity. RSC advances. 2024, vol. 14, str. 28423-28454, ilustr. ISSN 2046-2069. https://pubs.rsc.org/en/content/articlehtml/2024/ra/d4ra04802d, Repository of the University of Ljubljana – RUL , DOI: 10.1039/d4ra04802d. [COBISS.SI-ID 206901507]
project: This work was supported by the Slovenian Research Agency (Grant No. P1-0208, J1-3021 and J1-3031), the Research Council of Finland (Grant No. 321551) and the following research grants in Hungary: National Laboratory of Biotechnology Grant 2022- 2.1.1-NL-2022-00008 (C. P.) and National Research, Development and Innovation Office K146323.

30. RAJU, Liju, BENEDETTO TIZ, Davide, ILES, Adrian, KOŠMRLJ, Janez, JANSEN-VAN VUUREN, Ross D. Deuteration of six-membered N-heteroarenes : chemistry and applications. Chemistry : a European journal. [Print ed.]. 1 Dec. 2025, vol. 31, iss. 67, [article no.] e02659, str. 1-55, ilustr. ISSN 0947-6539. https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202502659, Repository of the University of Ljubljana – RUL , DOI: 10.1002/chem.202502659. [COBISS.SI-ID 255671299]