Igor Legen

1. LEGEN, Igor. Proučevanje prehoda aciklovirja skozi izolirano črevo podgane v pogojih in vitro = The study of acyclovir transport through isolated rat small intestine in vitro. In: JAPELJ, Miha (ed.). Zbornik povzetkov = Book of abstracts. Mednarodni simpozij Krkini raziskovalni dnevi in XXVIII. Krkine nagrade, Novo mesto, 28. in 29. oktober 1998. Novo mesto: Krka, 1998. Str. 42. [COBISS.SI-ID 388977]

2. LEGEN, Igor. Proučevanje prehoda nekaterih derivatov aciklovirja skozi jejunum podgane in različne disperzije mucinov = The study of some acyclovir derivatives transport through rat jejunum and different dispersions of mucins : diplomska naloga. Ljubljana: [I. Legen], 1998. 90 f., tabele. Fakulteta za farmacijo, Ljubljana, Diplomske naloge, 1388. [COBISS.SI-ID 359537]

1999

3. LEGEN, Igor, KRISTL, Albin. Hydrolipophilic properties of some guanine derivatives and their permeability through rat jejunum and mucus dispersions. In: MRHAR, Aleš (ed.). 3rd Central European Symposium on Pharmaceutical Technology, September 23-24, 1999, Portorož, Slovenia : proceedings from the Symposium. 3rd Central European Symposium on Pharmaceutical Technology, September 23 - 24, 1999, Portorož, Slovenia. Ljubljana: Slovensko farmacevtsko Društvo, 1999. Str. 348-349. Farmacevtski vestnik, Let. 50, posebna št. 2. ISSN 0014-8229. [COBISS.SI-ID 556145]

4. KRISTL, Albin, LEGEN, Igor. Mucus/mucin dispersions as a model for drug absorption. In: MRHAR, Aleš (ed.). 3rd Central European Symposium on Pharmaceutical Technology, September 23-24, 1999, Portorož, Slovenia : proceedings from the Symposium. 3rd Central European Symposium on Pharmaceutical Technology, September 23 - 24, 1999, Portorož, Slovenia. Ljubljana: Slovensko farmacevtsko Društvo, 1999. Str. 270-271. Farmacevtski vestnik, Let. 50, posebna št. 2. ISSN 0014-8229. [COBISS.SI-ID 552561]

5. KRISTL, Albin, LEGEN, Igor. The transport of some acyclovir derivatives through rat jejunum and mucus dispersions. In: Fifth Congress of the European Federation of Pharmaceutical Sciences (EUFEPS) : abstracts from "mechanistically-based drug design and development: integrating the biological revolution". Meeting held in Jerusalem, Israel, April 25-30, 1999. Amsterdam: Elsevier, 1999. Str. xxvi. European Journal of Pharmaceutical Sciences, Vol. 8/2. ISSN 0928-0987. [COBISS.SI-ID 485745]

2000

6. LEGEN, Igor, KRISTL, Albin. Comparison of two different types of side-by-side diffusion cells. In: 3rd International Intensive and Workshop on Cell Culture and other AlternativeMethods for Drug delivery Research, February 23-March 3, 2000. Saarbrücken: [s.n.], 2000. [1] f. [COBISS.SI-ID 628081]

7. KRISTL, Albin, LEGEN, Igor. Lipophilicity, permeability and transport of some antiviral compounds through the intestinal absorption barriers. In: Lipophilicity in Drug Disposition : the second logP Symposium : practical and computational approaches to molecular properties related to drug permeation, disposition and metabolism : programme and abstracts, Lausanne, March 5-9, 2000. Zurich: Wiley, 2000. Str. o-a5. [COBISS.SI-ID 627569]

2001

8. LEGEN, Igor, KRISTL, Albin. Comparative permeability of some acyclovir derivatives through native mucus and crude mucin dispersions. Drug development and industrial pharmacy. 2001, vol. 27, no. 7, str. 669-674. ISSN 0363-9045. [COBISS.SI-ID 999281]

9. KRISTL, Albin, LEGEN, Igor. Lipophilicity, permeability and transport of some antiviral barriers. In: TESTA, Bernard (ed.). Pharmacokinetic optimization in drug research : biological, physicochemical, and computational strategies. Weinheim [etc.]: Verlag Helvetica Chimica Acta, 2001. ISBN 3-906390-22-5. [COBISS.SI-ID 1015153]

10. LEGEN, Igor, KRISTL, Albin. Passive transport of ketoprofen across rat jejunum in vitro. In: 4th Central European Symposium on Pharmaceutical Technology : abstracts of the Plenary Lecture, Short Lectures and Posters of the 16th Scientific Congress of the Austrian Pharmaceutical Society together with 4th Central European Symposium on Pharmaceutical Technology, September 23 to September 25, 2001, Vienna. Wien: Österreichische Pharmazeutische Gesellschaft, 2001. Str. s292-s293. Scientia Pharmaceutica, Bd. 69, Hft 3, suppl. 1. ISSN 0036-8709. [COBISS.SI-ID 983409]

11. KRISTL, Albin, LEGEN, Igor. Polarised transport of monocarboxylic acid type drugs across rat jejunum in vitro: the effect of mucolysis and ATP-depletion. In: 4th Central European Symposium on Pharmaceutical Technology : abstracts of the Plenary Lecture, Short Lectures and Posters of the 16th Scientific Congress of the Austrian Pharmaceutical Society together with 4th Central European Symposium on Pharmaceutical Technology, September 23 to September 25, 2001, Vienna. Wien: Österreichische Pharmazeutische Gesellschaft, 2001. Str. s123-s124. Scientia Pharmaceutica, Bd. 69, Hft 3, suppl. 1. ISSN 0036-8709. [COBISS.SI-ID 980593]

2002

12. KRISTL, Albin, LEGEN, Igor. Characteristics Of Ketoprofen Transport Through Rat Jejunum 'in Vitro'. 2002. [1.] str. AAPSPharmSci, Vol. 4, No. 4, Abstract R6154 (2002. ISSN 1522-1059. http://www.aapsj.org/abstracts/AM_2002/AAPS2002-002250.pdf. [COBISS.SI-ID 1241713]

13. LEGEN, Igor, KRISTL, Albin. Characteristics Of Ketoprofen Transport Through Rat Jejunum 'in Vitro'. In: AAPS AAPS Annual Meeting and Exposition, november 10-14, 2002, Toronto, Ontario, Canada : final program. [S.l.: s.n.], 2002. [1.] str. [COBISS.SI-ID 1415793]

14. LEGEN, Igor, KRISTL, Albin. Ketoprofen-induced intestinal permeability changes studied in side-by-side diffusion cells. Journal of Pharmacy and Pharmacology. 2002, vol. 54, no. 10, str. 1419-1422. ISSN 0022-3573. [COBISS.SI-ID 1181041]

2003

15. LEGEN, Igor. Absorpcijske bariere za monokarboksilne učinkovine v tankem črevesu : doktorska disertacija = Absorption barriers for monocarboxylic drugs in the small intestine. Ljubljana: [Legen I.], 2003. 128 f., ilustr. Fakulteta za farmacijo, Ljubljana, Doktorske disertacije, 38. [COBISS.SI-ID 1379185]

16. SALOBIR, Mateja, LEGEN, Igor, KERČ, Janez. Comparison of different intestinal epithelia as models for absoption enhancement studies. In: MRHAR, Aleš (ed.). Proceedings from the symposium. Ljubljana: Slovensko farmacevtsko društvo: = Slovenian Pharmaceutical Society, 2003. Str. 541-542. Farmacevtski vestnik, let. 54, special issue. ISSN 0014-8229. [COBISS.SI-ID 1367153]

17. LEGEN, Igor, KRISTL, Albin. Factors affecting the microclimate pH of the rat jejunum in ringer bicarbonate buffer. Biological & pharmaceutical bulletin. 2003, vol. 26, no. 6, str. 886-889. ISSN 0918-6158. [COBISS.SI-ID 1327729]

18. ŽAKELJ, Simon, LEGEN, Igor, KRISTL, Albin. The influence of HCO3 free incubation salines on rat jejunal tissue in side-by-side diffusion chambers. In: MRHAR, Aleš (ed.). Proceedings from the symposium. Ljubljana: Slovensko farmacevtsko društvo: = Slovenian Pharmaceutical Society, 2003. Str. 529-530. Farmacevtski vestnik, let. 54, special issue. ISSN 0014-8229. [COBISS.SI-ID 1366641]

19. LEGEN, Igor, KRISTL, Albin. Multidrug resistance associated protein 2 (MRP2) activity in the rat small intestine in vitro. In: MRHAR, Aleš (ed.). Proceedings from the symposium. Ljubljana: Slovensko farmacevtsko društvo: = Slovenian Pharmaceutical Society, 2003. Str. 343-344. Farmacevtski vestnik, let. 54, special issue. ISSN 0014-8229. [COBISS.SI-ID 1361009]

20. LEGEN, Igor, KRISTL, Albin. Multidrug resistance associated protein 2 (MRP2) as a potential site for drug-drug interactions in the small intestine. In: 1st EUFEPS Conference on Optimising Drug Delivery and Formulation: New Challenges in Drug Delivery : final programme and abstracts : Palais des Congres de Versailles, France, September 29 - October 1, 2003. [S.l.: s.n], 2003. Str. 108. [COBISS.SI-ID 1370225]

21. LEGEN, Igor, KRISTL, Albin. pH and energy dependent transport of ketoprofen across rat jejunum in vitro. European journal of pharmaceutics and biopharmaceutics. [Print ed.]. 2003, vol. 56, no. 1, str. 87-94. ISSN 0939-6411. [COBISS.SI-ID 1327473]

22. LEGEN, Igor, ŽAKELJ, Simon, KRISTL, Albin. Polarised transport of monocarboxylic acid type drugs across rat jejunum in vitro. International journal of pharmaceutics. [Print ed.]. 2003, vol. 256, no. 1-2, str. 161-166. ISSN 0378-5173. [COBISS.SI-ID 1282417]

2004

23. LEGEN, Igor, KRISTL, Albin. D-glucose triggers multidrug resistance-associated protein (MRP)-mediated secretion of fluorescein across rat jejunum in vitro. Pharmaceutical research. [Print ed.]. 2004, vol. 21, no. 4, str. 635-640, graf. prikazi. ISSN 0724-8741. [COBISS.SI-ID 1495409]

24. ŽAKELJ, Simon, LEGEN, Igor, VEBER, Marjan, KRISTL, Albin. The influence of buffer composition on tissue integrity during permeability experiments "in vitro". International journal of pharmaceutics. [Print ed.]. 2004, vol. 272, no. 1-2, str. 173-180. ISSN 0378-5173. [COBISS.SI-ID 1472113]

2005

25. LEGEN, Igor, SALOBIR, Mateja, KERČ, Janez. Comparison of different intestinal epithelia as models for absorption enhancement studies. International journal of pharmaceutics. [Print ed.]. 2005, vol. 291, str. 183-188, graf. prikazi. ISSN 0378-5173. [COBISS.SI-ID 2286001]

26. LEGEN, Igor, KRAČUN, Matjaž, SALOBIR, Mateja, KERČ, Janez. The influence of some pharmaceutically acceptable excipients on the permeability of amoxicillin across the rat jejunum in vitro. In: 6th Central European Symposium on Pharmaceutical Technology and Biotechnology, May 25-27, 2005, Siófok, Hungary : abstract supplement. Amsterdam: Elsevier, 2005. Str. s148-s149. European Journal of Pharmaceutical Sciences, Vol. 25, suppl. 1. ISSN 0928-0987. [COBISS.SI-ID 1740913]

2006

27. LEGEN, Igor, KRAČUN, Matjaž, SALOBIR, Mateja, KERČ, Janez. The evaluation of some pharmaceutically acceptable excipients as permeation enhancers for amoxicillin. International journal of pharmaceutics. [Print ed.]. 2006, no. 1-2, vol. 308, str. 84-89, graf. prikazi. ISSN 0378-5173. [COBISS.SI-ID 1260124]

2007

28. STARIČ, Rok. Razvoj in vrednotenje novega dostavnega sistema na osnovi suhih mikroemulzij = Development and evaluation of new dry microemulsion based drug delivery system : diplomska naloga. Ljubljana: [R. Starič], 2007. 69 f., 6 f. pril., ilustr. Diplomske naloge. [COBISS.SI-ID 2092401]

29. PREŽELJ, Andrej, PLANTAN, Ivan, VILFAN, Gregor, ŠTEFANIČ, Petra, SELIČ, Lovro, IGLIČAR, Petra, CAR, Vjekoslava, ANDRENŠEK, Samo, LEGEN, Igor, NOVAK, Polona, ČERNE, Manica, URLEB, Uroš, LOCATELLI, Igor, MRHAR, Aleš, KOVAČIĆ, Nataša. Stability of 10-ethylidene trinems, PK of LK-157 and design of prodrug esters. In: 47th interscience conference on antimicrobial agents and chemotherapy : 47th ICAAC : September 17-20, 2007, McCormick Place, Chicago, IL USA : abstracts. Washington: American society for microbiology, 2007. Str. 222. [COBISS.SI-ID 1339228]

2008

30. STARIČ, Rok, LEGEN, Igor, JURKOVIČ, Polona, KERČ, Janez. Development and evaluation of new solid state microemulsion based drug delivery system. In: MRHAR, Aleš (ed.), BAUMGARTNER, Saša (ed.). 7th Central European Symposium on Pharmaceutical Technology and Biodelivery Systems, September 18-20, 2008, Hotel Mons, Ljubljana, Slovenia : Proceedings from the Symposium. Ljubljana: Slovenian Pharmaceutical Society, 2008. Str. 72-74. Farm. vestn., Let. 59, special iss. ISSN 0014-8229. [COBISS.SI-ID 1382236]

31. MARKUN, Boštjan, LEGEN, Igor, KOČEVAR, Klemen. Modeling dissolution of drugs in stomach environment. In: Tenth international workshop on physical characterization of pharmaceutical solids. Munster: ASSA, 2008. Str. 68. [COBISS.SI-ID 1351004]

32. MARKUN, Boštjan, LEGEN, Igor. Modelling dissolution of weakly basic drugs in physiological environment. In: MRHAR, Aleš (ed.), BAUMGARTNER, Saša (ed.). 7th Central European Symposium on Pharmaceutical Technology and Biodelivery Systems, September 18-20, 2008, Hotel Mons, Ljubljana, Slovenia : Proceedings from the Symposium. Ljubljana: Slovenian Pharmaceutical Society, 2008. Str. 182-183. Farm. vestn., Let. 59, special iss. ISSN 0014-8229. [COBISS.SI-ID 1415260]

33. BURJAK, Mateja, LEGEN, Igor, KERČ, Janez. Orally disintegrating tablets : WO 2008/077813 (A2) : international publication date 3 July 2008 (03.07.2008). München: World Intellectual Property Organization, 2008. . [COBISS.SI-ID 1402972]

2009

34. LEGEN, Igor. Kritični pogled na teste raztapljanja. In: 21. simpozij Sekcije farmacevtskih tehnologov : Povečanje topnosti in hitrosti raztapljanja težko topnih učinkovin : zbornik predavanj : Ljubljana, 18. junij 2009. Ljubljana: Slovensko farmacevtsko društvo, 2009. Str. 105-113. [COBISS.SI-ID 2610033]

35. IGLIČAR, Petra, LEGEN, Igor, VILFAN, Gregor, SELIČ, Lovro, PREŽELJ, Andrej. Permeability of a novel ß-lactamase inhibitor LK-157 and its ester prodrugs across rat jejunum in vitro. Journal of Pharmacy and Pharmacology. 2009, vol. 61, no. 9, str. 1211-1218, graf. prikazi. ISSN 0022-3573. DOI: 10.1211/jppž61.09.0011_. [COBISS.SI-ID 1420380]

36. LEGEN, Igor, BURJAK, Mateja. Pharmaceutical composition comprising at least one active agent and a binder, which swells in an acidic media : WO 2009/074517 (A1) : international publication date 18 June 2009 (18.06.2009). München: World Intellectual Property Organization, 2009. 26 str. [COBISS.SI-ID 1423708]

37. LEGEN, Igor, JERALA-ŠTRUKELJ, Zdenka, INJAC, Rade. Single dosage pharmaceutical formulation comprising eprosartan mesylate : US2011135738 (A1), 2011-06-09. München: World Intellectual Property Organization, 2009. 16 str. [COBISS.SI-ID 1423452]

2010

38. HUMAR, Vlasta, BESO, Adnan, LEGEN, Igor, BURJAK, Mateja. Active coating of pharmaceutical dosage forms : WO 2010081824 (A2) : international publication date 22 July 2010. München: World Intellectual Property Organization, 2010. 39 str. [COBISS.SI-ID 1485404]

39. KLANČAR, Uroš, JURKOVIČ, Polona, LEGEN, Igor, HORVAT, Matej. Extended release formulation comprising indapamide : EP2380561 (A1), 2011-10-26. München: European Patent Office, 2010. 1 f. [COBISS.SI-ID 1756667]

40. KLANČAR, Uroš, LEGEN, Igor, HORVAT, Matej. In vitro evaluation of extended release HPMC matrix tablets and correlation with in vivo data. In: Abstracts of the 8th Central European Symposium on Pharmaceutical Technology (CESPT), Satellite Symposium: 4th International Graz Congress on Pharmaceutical Engineering, September 16th-18th, Graz, Austria. 8th Central European Symposium on Pharmaceutical Technology (CESPT), Satellite Symposium: 4th International Graz Congress on Pharmaceutical Engineering, September 16th-18th, Graz, Austria. Wien: Österreichischer Apothekerverlag, 2010. Str. 611. Scientia Pharmaceutica, vol. 78, iss. 3. ISSN 0036-8709. [COBISS.SI-ID 1609467]

41. KLANČAR, Uroš, LEGEN, Igor, KRISTL, Albin, MRHAR, Aleš. "In vitro-in vivo" korelacija (IVIVC) za učinkovine v pripravkih s podaljšanim sproščanjem, ki se intenzivno metabolizirajo ali absorbirajo s prenašalci v prebavilih = In vitro in vivo correlation (IVIVC) for drugs in extended release formulations which are extensively metabolized or absorbed with transporters. Farmacevtski vestnik : strokovno glasilo slovenske farmacije. [Tiskana izd.]. 2010, letn. 61, št. 3, str. 162-170. ISSN 0014-8229. http://www.sfd.si/modules/catalog/products/prodfile/fv_3_2010_nr.pdf, Digitalna knjižnica Slovenije - dLib.si. [COBISS.SI-ID 2829169]

42. LEGEN, Igor. Optimising the use of dissolution testing in generic drug development : 2nd annual Dissolution testing, 19-20 October 2010, NH Pódium, Barcelona, Spain : predavanje. Barcelona, 2010. [COBISS.SI-ID 1486684]

2011

43. JERALA-ŠTRUKELJ, Zdenka, LEGEN, Igor, REVEN, Sebastjan. A pharmaceutical composition comprising eszopiclone : EP 1 997 482 B1 : date of publication and mention of the grant of the patent: 06.07.2011. [S.l.]: European Patent Office, 2011. 9 str. [COBISS.SI-ID 1412188]
patent family: US2008299193 (A1) - 2008-12-04

44. BERGLEZ, Sandra, LEGEN, Igor. Biorelevant dissolution method for extended release product. In: 4th BBBB-Bosphorus International Conference on Pharmaceutical Sciences: New trends in drug discovery, delivery systems and laboratory diagnostics, Bled, Slovenia, 29 September-01 October 2011 : proceedings. Amsterdam ... [etc.]: Elsevier, 2011. Str. 99-100. European journal of Pharmaceutical Sciences, Vol. 44, suppl. 1. ISSN 0928-0987. [COBISS.SI-ID 1461340]

45. KLANČAR, Uroš, LEGEN, Igor, NOVAK, Polona. Controlled release composition comprising levetiracetam : WO 2011033024 (A1) : international publication date 24 March 2011 (24.03.2011). München: World Intellectual Property Organization, 2011. 23 str. [COBISS.SI-ID 1485916]

46. JERALA-ŠTRUKELJ, Zdenka, LEGEN, Igor. New pharmaceutical composition containing candesartan cilexetil as lipophilic crystalline substance : EP 1 843 754 B1 : date of publication and mention of the grant of the patent: 03.08.2011. [S.l.]: European Patent Office, 2011. 11 str. [COBISS.SI-ID 1410652]
patent family: JP2008528456 (T) - 2008-07-31; US2008118564 (A1) - 2008-05-22; WO2006079496 (A1) - 2006-08-03

47. BESO, Adnan, LEGEN, Igor, REVEN, Sebastjan. Pharmaceutical composition comprising hydrochlorothiazide and telmisartan : EP 2 029 112 B1 : date of publication and mention of the grant of the patent: 23.02.2011. [S.l.]: European Patent Office, 2011. 12 str. [COBISS.SI-ID 1411676]
patent family: WO2007144175 (A3) - 2008-10-02

48. AVANZO, Matej, ROZMAN PETERKA, Tanja, LEGEN, Igor. Pharmaceutical composition of olmesartan medoxomil : EP 1 891 952 B1 : date of publication and mention of the grant of the patent: 05.10.2011. [S.l.]: European Patent Office, 2011. 9 str. [COBISS.SI-ID 1411420]
patent family: WO2007128478 (A3) - 2008-02-07

49. LEGEN, Igor. Preskus sproščanja učinkovine iz trdnih farmacevtskih oblik - izkušnje iz farmacevtske industrije = Dissolution tests - experience from the pharmaceutical industry. In: JEZERŠEK, Mirjam (ed.). [Zbornik prispevkov]. Strokovno posvetovanje ob predstavitvi tretje izdaje Formulariuma Slovenicuma (FS 3.0), Ljubljana, [oktober] 2-11. Ljubljana: Javna agencija RS za zdravila in medicinske pripomočke, 2011. Str. 28-34. ISBN 978-961-6383-28-8. [COBISS.SI-ID 1486940]

50. LEGEN, Igor, KERČ, Janez, JURKOVIČ, Polona. Self-microemulsifying drug delivery systems : EP 2 101 729 B1 : date of publication and mention of the grant of the patent: 30.03.2011. [S.l.]: European Patent Office, 2011. 28 str. [COBISS.SI-ID 1402716]
patent family: EP1961412 (A1) - 2008-08-27

51. REVEN, Sebastjan, LEGEN, Igor, JERALA-ŠTRUKELJ, Zdenka. Sirolimus formulation : US 8,053,444 (B2), 2011-11-08. Alexandria: United States Patent and Trademark Office, 2011. 5 str. [COBISS.SI-ID 1411932]
patent family: EP1952807 (A1) - 2008-08-06; US2008176888 (A1) - 2008-07-24

52. LEGEN, Igor. Use of physiologically based pharmacokinetic (PBPK) models for establishing invivo in vitro correlation for extended release formulation. In: 4th BBBB-Bosphorus International Conference on Pharmaceutical Sciences: New trends in drug discovery, delivery systems and laboratory diagnostics, Bled, Slovenia, 29 September-01 October 2011 : proceedings. Amsterdam ... [etc.]: Elsevier, 2011. Str. 102-103. European journal of Pharmaceutical Sciences, Vol. 44, suppl. 1. ISSN 0928-0987. [COBISS.SI-ID 1461084]

53. TRIPAR, Ana. Vrednotenje dveh različnih označevalcev paracelularnega prehoda pri poskusih permeabilnosti na izoliranem črevesju podgane = Evaluation of two different markers of paracellular transport in permeability studies on isolated rat small intestine : diplomska naloga. Ljubljana: [A. Tripar], 2011. 72 f., tabele. http://www.ffa.uni-lj.si/fileadmin/datoteke/Knjiznica/diplome/2011/Tripar_Ana_dipl_nal_2011.pdf, Repozitorij Univerze v Ljubljani – RUL. [COBISS.SI-ID 3161969]

2012

54. PETERNEL, Luka, KRISTAN, Katja, PETRUŠEVSKA, Marija, LANIŠNIK-RIŽNER, Tea, LEGEN, Igor. Suitability of isolated rat jejunum model for demonstration for BCS-based biowaiver request. Journal of pharmaceutical sciences. 2012, vol. 101, issue 4, str. 1436-1449. ISSN 0022-3549. DOI: 10.1002/jps.23027. [COBISS.SI-ID 1477468]

2013

55. ABRAMOVIĆ, Zrinka, JERALA-ŠTRUKELJ, Zdenka, LEGEN, Igor, KLANČAR, Uroš. Controlled release pharmaceutical compositions comprising O-desmethyl-venlafaxine : EP 2 367 536 (B1) - 2013-01-23 : date of publication and mention of the grant of the patent: 23.1.2013. München: European Patent Office, 2013. 19 str. [COBISS.SI-ID 1485660]

56. KLANČAR, Uroš, LEGEN, Igor. Dissolution apparatus comprising beads and process : EP2320227 (B1) : date of publication and mention of the grant of the patent 20.02.2013. [Berlin]: European Patent Office, 2013. 18 str. [COBISS.SI-ID 1486172]

57. KLANČAR, Uroš, MARKUN, Boštjan, BAUMGARTNER, Saša, LEGEN, Igor. A novel beads-based dissolution method for the in vitro evaluation of extended release HPMC matrix tablets and the correlation with the in vivo data. The AAPS Journal. 2013, vol. 15, no. 1, str. 267-277. ISSN 1550-7416. http://link.springer.com/article/10.1208%2Fs12248-012-9422-x, DOI: 10.1208/s12248-012-9422-x. [COBISS.SI-ID 3359601]

58. JURINČIČ, Valentina. Ovrednotenje metode pretočne celice za spremljanje sproščanja težko topne učinkovine iz farmacevtske oblike s takojšnjim sproščanjem = Evaluation of the flow through cell method for monitoring the release of a poorly soluble drug from an immediate release dosage form : [diplomska naloga]. Ljubljana: [V. Jurinčič], 2013. III, 72 f., tabele, graf. prikazi. http://www.ffa.uni-lj.si/fileadmin/datoteke/Knjiznica/diplome/2013/Jurincic_Valentina_dipl_nal_2013.pdf, Repozitorij Univerze v Ljubljani – RUL. [COBISS.SI-ID 3427697]

59. KLANČAR, Uroš. Razvoj fiziološko relevantnih metod preskusa raztapljanja hidrofilnih ogrodnih tablet z uporabo farmakopejskih naprav ter njihovih modifikacij = Development of the physiologically relevant dissolution tests for evaluation of hydrophilic matrix tablets using pharmacopoeial apparatuses and their modifications : doktorska disertacija. Ljubljana: [U. Klančar], 2013. 173 str., ilustr. [COBISS.SI-ID 267110400]

2014

60. LEGEN, Igor, KUHAR, Polonca. Coated formulations for tolterodine : US8642078 (B2) : international publication date 4th February 2014. Aleksandria: United States Patent and Trademark Office, 2014. 7 str. [COBISS.SI-ID 1410908]
patent family: WO2007113207 (A3) - 2008-09-25; EP2001444 (A2) - 2008-12-17; EP1839649 (A1) - 2007-10-03; CA2647765 (A1) - 2007-10-11

61. KLANČAR, Uroš, MARKUM, B., LEGEN, Igor. Development of physiologically relevant dissolution methods for evaluation of hydrophilic matrix tablets using new dissolution apparatus : [10th Central European Symposium on Pharmaceutical Technology, September 18-20, 2014, Portorož, Slovenia]. Farmacevtski vestnik : strokovno glasilo slovenske farmacije. [Tiskana izd.]. 2014, letn. 65, spec. iss., str. 37-39. ISSN 0014-8229. [COBISS.SI-ID 28128807]

62. OPARA, Jerneja, LEGEN, Igor. Neuro-fuzzy models as an IVIVR tool and their applicability in generic drug development. The AAPS Journal. 2014, vol. 16, issue 2, str. 324-334. ISSN 1550-7416. DOI: 10.1208/s12248-014-9569-8. [COBISS.SI-ID 1553244]

63. LEGEN, Igor, PETERNEL, Luka, NOVAK ŠTAGOJ, Mateja, HOMAR, Miha, ROZMAN PETERKA, Tanja, KLANČAR, Uroš. Self-microemulsifying drug delivery system of abiraterone or abiraterone acetate : WO2014009434 (A1), 2014-01-16. Geneve: World Intellectual Property Organization, International Bureau, 2014. 43 str. [COBISS.SI-ID 1551452]

2015

64. PETRUŠEVSKA, Marija, BERGLEZ, Sandra, KRISCH, Igor, LEGEN, Igor, MEGUŠAR, Klara, PETERNEL, Luka, et al. Biowaiver monographs for immediate release solid oral dosage forms: levetiracetam. Journal of pharmaceutical sciences. 2015, vol. 104, iss. 9, str. 2676-2687, ilustr. ISSN 0022-3549. DOI: 10.1002/jps.24350. [COBISS.SI-ID 17401091]

65. LEGEN, Igor, KUHAR, Polonca. Coated formulations : EP 1 978 935 B1 : Date of publication and mention of the grant of the patent: 07.01.2015. Genève: European Patent Office, 2015. 21 str. [COBISS.SI-ID 1411164]
patent family: EP1978935 (A1) 2008-10-15; EP1810668 (A1) - 2007-07-25; WO2007082770 (A1) - 2007-07-26; CA2637444 (A1) - 2007-07-26; CA 2637444 (C), 2015-04-14

66. KLANČAR, Uroš, BAUMGARTNER, Saša, LEGEN, Igor, NOVAK, Polona, JERAJ, Nataša, KRAJCAR, Dejan, MARKUN, Boštjan, KOČEVAR, Klemen. Determining the polymer threshold amount for achieving robust drug release from HPMC and HPC matrix tablets containing a high-dose BCS class I model drug : in vitro and in vivo studies. AAPS PharmSciTech. [Online ed.]. 2015, vol. 16, issue 2, str. 398-406, tabele, graf. prikazi. ISSN 1530-9932. http://link.springer.com/article/10.1208%2Fs12249-014-0234-4, DOI: 10.1208/s12249-014-0234-4. [COBISS.SI-ID 3750001]

67. LEGEN, Igor, KOČEVAR, Klemen. Two-compartment dissolution apparatus and process : EP2347242 (B1) - 2015-09-23. [Berlin]: European Patent Office, 2015. 18 str. [COBISS.SI-ID 1485148]

2016

68. OMERZU, Petra. Optimizacija pogojev v novem modelu za sproščanje v želodcu in primerjava rezultatov izbranih oblik z in vivo podatki ter testom z napravo II po ameriški farmakopeji = Optimization of conditions in the new stomach dissolution model and comparison of the results of selected formulation with in vivo data and a test with the device II according to the US Pharmacopoeia : enoviti magistrski študij farmacije. Ljubljana: [P. Omerzu], 2016. V, 55 f., tabele, ilustr. http://www.ffa.uni-lj.si/docs/default-source/knjiznica-doc/magistrske/omerzu_petra_mag_nal_2016.pdf?sfvrsn=2, Repozitorij Univerze v Ljubljani – RUL. [COBISS.SI-ID 4246641]

2017

69. HRIBAR, Melita, TRONTELJ, Jurij, KLANČAR, Uroš, MARKUN, Boštjan, ČELIGOJ DUJC, Tanja, LEGEN, Igor. A novel intestine model apparatus for drug dissolution capable of simulating the peristaltic action. AAPS PharmSciTech. [Online ed.]. 2017, vol. 18, iss. 5, str. 1646-1656, ilustr. ISSN 1530-9932. https://link.springer.com/article/10.1208%2Fs12249-016-0629-5, https://link.springer.com/content/pdf/10.1208%2Fs12249-016-0629-5.pdf, DOI: 10.1208/s12249-016-0629-5. [COBISS.SI-ID 4225137]

70. ČREŠNIK, Maja. Ovrednotenje različnih medijev in silikonskih vreč za izvedbo preskusa sproščanja izbranih vzorcev trdih kapsul na napravi za posnemanje želodčnega gibanja = Evaluation of different media and silicone bags for implementation of dissolution testing of selected samples of hard capsules on an apparatus simulating the movement of human stomach : magistrski študijski program Industrijska farmacija. Ljubljana: [M. Črešnik], 2017. X, 60 f., tabele. http://www.ffa.uni-lj.si/docs/default-source/knjiznica-doc/magistrske/2017/cresnik_maja_mag_nal_2017.pdf?sfvrsn=2, Repozitorij Univerze v Ljubljani – RUL. [COBISS.SI-ID 4365681]

71. VOUK, Anja. Vrednotenje sproščanja učinkovin iz mehansko različno občutljivih farmacevtskih oblik na napravi za posnemanje črevesnega gibanja = Evaluation of drug release from mechanically variably sensitive dosage forms on an apparatus simulating the movement of human intestine : enoviti magistrski študij farmacije. Ljubljana: [A. Vouk], 2017. VII, 51 f., tabele, ilustr. http://www.ffa.uni-lj.si/docs/default-source/knjiznica-doc/magistrske/2017/vouk_anja_mag_nal_2017.pdf?sfvrsn=2, Repozitorij Univerze v Ljubljani – RUL. [COBISS.SI-ID 4396401]

2018

72. LEGEN, Igor, BEVC, Alenka, BERGLEZ, Sandra, DIACI, Janez, KUŠČER, Lovro. Apparatus for simulating the function of human stomach and/or human intestine : United States patent US10127839 (B2), 2018-11-13. Alexandria: United States Patent and Trademark Office, 2018. 25 str. [COBISS.SI-ID 1584732]
patent family: US2016351079 (A1), 2016-12-01; EP13196935, 2013-12-12; EP3080793 (B1), 2018-11-14; EP2884480 (A1), 2015-06-17; WO2015086769 (A1), 2015-06-18

73. HRIBAR, Melita, JAKASANOVSKI, Ognen, TRONTELJ, Jurij, GRABNAR, Iztok, LEGEN, Igor. Determining the pressure-generating capacity of the classical and alternative in vitro dissolution methods using a wireless motility capsule. Journal of pharmaceutical innovation. 2018, vol. 13, iss. 3, str. 226-236, ilustr. ISSN 1939-8042. DOI: 10.1007/s12247-018-9317-1. [COBISS.SI-ID 1444958]

2019

74. ADAMER, Verena, JEREB, Rebeka, LEGEN, Igor, et al. Crystalline form II of darolutamide : WO2019166385A1 - 2019-09-06. Geneva: World Intellectual Property Organization, 2019. 59 str., ilustr. [COBISS.SI-ID 22706179]

75. HRIBAR, Melita, TRONTELJ, Jurij, BERGLEZ, Sandra, BEVC, Alenka, KUŠČER, Lovro, DIACI, Janez, LEGEN, Igor. Design of an innovative advanced gastric simulator. Dissolution technologies. 2019, vol. 26, iss. 4, str. 20-29, ilustr. ISSN 1521-298X. DOI: 10.14227/DT260219P20. [COBISS.SI-ID 1482846]

76. JEREB, Rebeka, OPARA, Jerneja, LEGEN, Igor, PETEK, Boštjan, BAJC, Aleksander, ŽAKELJ, Simon, KRISTL, Albin. PBPK absorption modeling of food effect and bioequivalence in fed state for two formulations with crystalline and amorphous forms of BCS 2 class drug in generic drug development. AAPS PharmSciTech. [Online ed.]. 2019, vol. 20, issue 2, str. 1-10, ilustr. ISSN 1530-9932. https://link.springer.com/article/10.1208%2Fs12249-018-1285-8, DOI: 10.1208/s12249-018-1285-8. [COBISS.SI-ID 1454174]
project: P1-0189; funder: ARRS

77. MITRA, Amitava, PETEK, Boštjan, BAJC, Aleksander, VELAGAPUDI, Raja, LEGEN, Igor. Physiologically based absorption modeling to predict bioequivalence of controlled release and immediate release oral products. European journal of pharmaceutics and biopharmaceutics. [Print ed.]. 2019, vol. 134, str. 117-125, ilustr. ISSN 0939-6411. DOI: 10.1016/j.ejpb.2018.11.019. [COBISS.SI-ID 1445214]

78. KREFT, Klemen. Vrednotenje vpliva simulacije luminalnih pogojev želodca na gelsko plast ogrodnih tablet = Evaluation of the simulated stomach's luminal environment influences on the gel layer of the matrix tablets ; enoviti magistrski študij farmacija. Ljubljana: [K. Kreft], 2019. VIII, 60 f., graf. prikazi, tabele. https://repozitorij.uni-lj.si/IzpisGradiva.php?id=109143. [COBISS.SI-ID 4768369]

2020

79. BERGINC, Katja, SIBINOVSKA, Nadica, ŽAKELJ, Simon, TRONTELJ, Jurij, LEGEN, Igor. Biopharmaceutical classification of desloratadine - not all drugs are classified the easy way. Acta pharmaceutica. 2020, vol. 70, iss. 2, str. 131-144, ilustr. ISSN 1330-0075. https://sciendo.com/article/10.2478/acph-2020-0006, Repozitorij Univerze v Ljubljani – RUL, DOI: 10.2478/acph-2020-0006. [COBISS.SI-ID 4797553]
project: P1-0189; funder: ARRS

80. VRBANAC, Helena, TRONTELJ, Jurij, BERGLEZ, Sandra, PETEK, Boštjan, OPARA, Jerneja, JEREB, Rebeka, KRAJCAR, Dejan, LEGEN, Igor. The biorelevant simulation of gastric emptying and its impact on model drug dissolution and absorption kinetics. European journal of pharmaceutics and biopharmaceutics. [Print ed.]. 2020, vol. 149, str. 113-120, ilustr. ISSN 0939-6411. https://www.sciencedirect.com/science/article/pii/S0939641120300357, DOI: 10.1016/j.ejpb.2020.02.002. [COBISS.SI-ID 4884849]
project: P1-0189; funder: ARRS

81. JEREB, Rebeka, OPARA, Jerneja, LEGEN, Igor, PETEK, Boštjan, GRABNAR, Darja. In vitro - in vivo relationship and bioequivalence prediction for modified - release capsules based on a PBPK absorption model. AAPS PharmSciTech. [Online ed.]. 2020, vol. 21, iss. 1, str. 1-11, ilustr. ISSN 1530-9932. https://link.springer.com/article/10.1208%2Fs12249-019-1566-x, DOI: 10.1208/s12249-019-1566-x. [COBISS.SI-ID 4885105]

82. VRBANAC, Helena, TRONTELJ, Jurij, KALČIĆ, Špela, LEGEN, Igor. Mechanistic study of model drug release from HPMC matrices in fed gastric media. Journal of drug delivery science and technology. [Print ed.]. 2020, vol. 60, str. 1-9, ilustr. ISSN 1773-2247. https://www.sciencedirect.com/science/article/pii/S177322472031323X?via%3Dihub, DOI: 10.1016/j.jddst.2020.102034. [COBISS.SI-ID 28915203]
project: P1-0189; funder: ARRS

83. VRBANAC, Helena, TRONTELJ, Jurij, BERGLEZ, Sandra, KREFT, Klemen, KRAJCAR, Dejan, LEGEN, Igor. Simulated migrating motor complex and its impact on the release properties of hydrophilic matrix systems. Journal of drug delivery science and technology. [Print ed.]. 2020, vol. 55, str. 1-11, ilustr. ISSN 1773-2247. https://www.sciencedirect.com/science/article/pii/S1773224719305921?via%3Dihub, DOI: 10.1016/j.jddst.2019.101338. [COBISS.SI-ID 1554014]
project: P1-0189; funder: ARRS

84. VRBANAC, Helena, TRONTELJ, Jurij, BERGLEZ, Sandra, PETEK, Boštjan, OPARA, Jerneja, JEREB, Rebeka, KRAJCAR, Dejan, LEGEN, Igor. The biorelevant simulation of gastric emptying and its impact on model drug dissolution and absorption kinetics. In: Third ALL WGs UNGAP Meeting, 11th - 12th February 2020 : Ljubljana, Slovenia. Ljubljana: [s. n.], 2020. 1 str., ilustr. [COBISS.SI-ID 1553758]

85. KALČIČ, Špela. Vpliv sestavin hrane in različnih mehanskih obremenitev na sproščanje učinkovine iz hidrofilnih ogrodnih tablet = The influence of food components and various mechanical stresses on the drug release from hydrophilic matrix tablets : [Prešernove nagrade študentom]. Ljubljana: [Š. Kalčič], 2020. 89 f., tabele, ilustr. Prešernove nagrade študentom. [COBISS.SI-ID 41929475]

86. KALČIČ, Špela. Vpliv sestavin hrane in različnih mehanskih obremenitev na sproščanje učinkovine iz hidrofilnih ogrodnih tablet = The influence of food components and various mechanical stresses on the drug release from hydrophilic matrix tablets : magistrski študij industrijska farmacija. Ljubljana: [Š. Kalčič], 2020. XII, 79 str., tabele, ilustr. https://repozitorij.uni-lj.si/IzpisGradiva.php?id=117260. [COBISS.SI-ID 26046211]

2023

87. KRAJCAR, Dejan, JEREB, Rebeka, LEGEN, Igor, OPARA, Jerneja, GRABNAR, Iztok. Predictive potential of acido-basic properties, solubility and food on bioequivalence study outcome : analysis of 128 studies. Drugs in R&D. 2023, vol. 23, iss. 3, str. 211-220. ISSN 1179-6901. https://link.springer.com/article/10.1007/s40268-023-00426-6, Repozitorij Univerze v Ljubljani – RUL, DOI: 10.1007/s40268-023-00426-6. [COBISS.SI-ID 155412483]
project: P1-0189; funder: ARRS

88. KRAJCAR, Dejan, GRABNAR, Iztok, JEREB, Rebeka, LEGEN, Igor, OPARA, Jerneja. Predictive potential of BCS and pharmacokinetic parameters on study outcome : analysis of 198 In vivo bioequivalence studies. European journal of drug metabolism and pharmacokinetics. 2023, vol. 48, iss. 3, str. 241-255, ilustr. ISSN 2107-0180. https://link.springer.com/article/10.1007/s13318-023-00821-z, Repozitorij Univerze v Ljubljani – RUL, DOI: 10.1007/s13318-023-00821-z. [COBISS.SI-ID 144230403]

89. OLENIK, Katja. Simulacija migracijskega motoričnega kompleksa na napravi za posnemanje gibanja želodca = Simulation of migrating motor complex on advanced gastric simulator : enoviti magistrski študijski program Farmacija. Ljubljana: [K. Olenik], 2023. XI, 77 str., ilustr., graf. prikazi. [COBISS.SI-ID 145794051]